Biomedical subjects

A B Rendas

Publications and source records attributed to A B Rendas.

6 recordsLinked to original sources

PubMed2003

How do learning issues relate with content in a problem-based learning pathophysiology course?

The relation between learning process and content coverage is becoming increasingly important for the understanding of the effects of problem-based learning (PBL) on students' learning. In our medical school, PBL is used as a major educational strategy in the discipline of pathophysiology. A computer program was developed allowing students to register learning issues identified as needed during tutorial sessions and learning issues stated as covered during the individual study periods. In our study, we compared "planned" (learning issues identified during PBL sessions) and "accomplished" learning issues (covered after the independent study periods) identified by pathophysiology students from three consecutive years. We found that the planned learning issues raised during tutorial sessions related to the issues effectively accomplished during the independent study and that their number grew stepwise from basic to preclinical to clinical sciences. Pathophysiology was, globally, the most mentioned discipline. Moreover, the most mentioned disciplines from the basic, preclinical, and clinical areas were physiology, histopathology, and internal medicine, respectively. The single-discipline approach did not limit the student's capacity to identify and cover learning issues beyond the objectives of pathophysiology.

Education, Medical↗

PubMed1997

Methacholine dose-response slopes from maximal bronchial challenge tests in asthmatic children: methodological aspects.

To determine whether the slope of a maximal bronchial challenge test (in which FEV1 falls by over 50%) could be extrapolated from a standard bronchial challenge test (in which FEV1 falls up to 20%), 14 asthmatic children performed a single maximal bronchial challenge test with methacholine (dose range: 0.097-30.08 mumol) by the dosimeter method. Maximal dose-response curves were included according to the following criteria: (1) at least one more dose beyond a delta FEV1 > or = 20%; and (2) a MFEV1 > or = 50%. PD20 FEV1 was calculated, and the slopes of the early part of the dose-response curve (standard dose-response slopes) and of the entire curve (maximal dose-response slopes) were calculated by two methods: the two-point slope (DRR) and the least squares method (LSS) in % delta FEV1 x mumol-1. Maximal dose-response slopes were compared with the corresponding standard dose-response slopes by a paired Student's t test after logarithmic transformation of the data; the goodness of fit of the LSS was also determined. Maximal dose-response slopes were significantly different (p < 0.0001) from those calculated on the early part of the curve: DRR20% (91.2 +/- 2.7 delta FEV1%. mumol-1) was 2.88 times higher than DRR50% (31.6 +/- 3.4 delta FEV1%. mumol-1), and the LSS20% (89.1 +/- 2.8% delta FEV1. mumol-1) was 3.10 times higher than LSS50% (28.8 +/- 1.5% delta FEV1. mumol-1). The goodness of fit of LSS50% was significant in all cases, whereas LSS20% failed to be significant in one. These results suggest that maximal dose-response slopes cannot be predicted from the data of standard bronchial challenge tests.

Adolescent↗

PubMed1994

[The repercussions of pulmonary congestion on ventilatory volumes, capacities and flows].

OBJECTIVES: To evaluate the effects of pulmonary congestion on pulmonary function. STUDY DESIGN: Prospective study performed in patients with left ventricular failure or mitral stenosis. MATERIAL AND METHODS: Forty-eight hospitalized patients were included suffering from pulmonary congestion either from left ventricular failure or mitral stenosis. While in hospital all patients were submitted to right heart catheterization by the Swan-Ganz method and also to an echocardiographic examination. Within 48 hours after the patients were submitted to the following lung function studies: lung volumes and capacities by the multi-breath helium dilution method and airway flows by pneumotachography. Respiratory symptoms were evaluated by the Medical Research Council Questionnaire and the functional class classified according to the NYHA. Correlations were made between the functional and clinical data. RESULTS: Regarding the cardiac evaluation patients presented with a mean pulmonary wedge pressure of 19.9 +/- 8.6 mmHg, a cardiac index of 2.5 +/- 0.8 l/min/m2, an end diastolic dimension of the left ventricle of 65.9 +/- 10.1 mm, and end systolic dimension of 51.2 +/- 12.2 mm, with a shortening fraction of 21.8 +/- 9.5%. The pulmonary evaluation showed a restrictive syndrome with a reduction in the mean values of the following parameters: total pulmonary capacity 71 +/- 14.4% of the predicted value (pv), forced vital capacity (FVC) 69.8 +/- 20.5% pv, and forced expiratory volume (FEV1) of 64 +/- 21.8% vp. The index FEV1/FVC was within the normal value of 72.7 +/- 9.7%. These lung function results did not correlate significantly with either the clinical, the hemodynamic or echocardiographic findings. CONCLUSION: In these group of patients pulmonary congestion led to the development of a restrictive syndrome which failed to correlate in severity with the duration of the disease, the pulmonary wedge pressure and the left ventricular function.

Aged↗

PubMed1981

Morphology of the veins draining the coronary sinus of the dog.

The morphology of the superficial cardiac veins draining the coronary sinus was investigated in 47 normal adult dogs, using the injection-corrosion-fluorescence technique. The veins pertaining to the left coronary territory all drain directly to the coronary sinus and include the following vessels: the great coronary vein and its tributaries, the left posterior atrial and ventricular veins. The veins pertaining to the right coronary territory include the posterior interventricular vein and the small cardiac vein. A comparison with the human pattern was made, particularly regarding the number of interventricular septal branches and it was suggested that such a reduction in number in the dog could be due to a take-over from the Thebesian veins in the venous drainage of the interventricular septum.

Animals↗

PubMedDate not supplied

[Control of breathing].

The control system of breathing can be considered as a closed loop system, consisting of two subsystems: the controlling system and the controlled system. Both systems are defined by their input-output relationships. The controlling system is defined by the Respiratory Centers that are responsible for two separate, but overlapping, patterns: the automatic control pattern and the behavioral or voluntary control. In the controlling system the input is the blood gas value and the output is some parameters of ventilation. The controlled system is characterized by an input of ventilation and an output of blood gas values. In this closed loop system breathing is normally regulated by two anatomically distinct but functionally integrated elements, referred to as the metabolic and behavioral respiratory control systems. The metabolic control is concerned with blood gas homeostasis and the voluntary control relates with activities such as phonation and singing that use the ventilatory apparatus for purposes other than gas exchange.

Brain↗

PubMedDate not supplied

[Applications of problem-based learning in the basic medical curriculum].

This article describes a project, which took place between 1992 and 1994, on the application of problem-based learning to three disciplines of the basic medical curriculum: Biochemistry (1st year) Physiology (2nd year) and physiopathology (3rd year). The main objectives of the project were to bring teaching closer to the future professional reality, to stimulate critical thinking and to facilitate independent learning. Despite differences in content and in teaching materials, the trigger event for learning was information given within a clinical context which was further analyzed in small-group tutorial sessions. The project also included the training of the tutors and the development of audiovisual materials. Although no statistically significant differences were found in the final scores between students taught during this period and before, the first group reported a considerable increase in the motivation to learn which, in the case of Biochemistry, was important to change the passive attitude of most students on entering university. The project also helped to create the appropriate atmosphere for the establishment of an office for medical education in the medical school to support other innovations in the field. With this project we wished to contribute, with a concrete experience, to the reform of medical education in Portugal, by demonstrating that problem-based learning can be used in single disciplines without major changes in the basic curriculum.

Curriculum↗