Biomedical subjects

A B Rickett

Publications and source records attributed to A B Rickett.

7 recordsLinked to original sources

PubMed2004

Acute pancreatitis and its association with diabetes mellitus in children.

Acute pancreatitis is more common in childhood than has been appreciated previously. During acute attacks of pancreatitis, hyperglycaemia and glycosuria are not uncommon but permanent diabetes mellitus is rare. Acute pancreatitis can also be associated with diabetic ketoacidosis and the association between these two is of a two-way cause and effect relationship. Early imaging of the pancreas is recommended in children with severe prolonged abdominal pain.

Acute Disease↗

PubMed1998

Rothmund-Thomson syndrome complicated by osteosarcoma.

We describe the radiological features of Rothmund-Thomson syndrome, a rare condition of autosomal recessive inheritance, which is commonly associated with a generalised skeletal dysplasia. The condition has an increased incidence of malignancy, which occasionally manifests in the musculoskeletal system.

Child↗

PubMed1996

An investigation into perihilar inflammatory change on the chest radiographs of children admitted with acute respiratory symptoms.

PURPOSE: To determine the incidence, correlation with selected parameters and interobserver variability of radiographic perihilar inflammatory change (PIC) in previously well children under 3 years of age, who were hospitalized with acute respiratory symptoms. PATIENTS AND METHODS: A total of 113 previously well children under 3 years of age who were hospitalized with acute respiratory symptoms, and whose chest radiographs (CRGs) showed no focal pulmonary abnormality, were prospectively identified. The CRGs were read blindly by two radiologists. Each scored the degree of PIC on a five point scale as absent (0), borderline/equivocal/indeterminate (1), mild but definite (2), moderate (3) and severe (4). RESULTS: PIC was read as definitely present (mean PIC score greater than or equal to 2) in 65 (58%) patients. The mean PIC score correlated with overinflation (r = 0.45, P < 0.01) and patient temperature (r = 0.22, P < 0.05). The mean PIC score was significantly higher (2.1 vs 1.5, P < 0.01) in those receiving antibiotics (n = 69). It was also significantly higher (2.4 vs 1.7, P < 0.01) in those receiving supplemental oxygen (n = 26). PIC was not associated with duration of admission, presence of wheeze (n = 79), use of nebulized bronchodilators (n = 61) or RSV positivity (n = 32). The k value for interobserver variability indicated only fair agreement (k = 0.29) between the two readers on the five point scale and moderate agreement (k = 0.41) when the data was pooled into two groups (0 and 1 vs 2, 3 and 4). CONCLUSIONS: PIC is a common radiographic finding in children under 3 years of age who are hospitalized with acute respiratory symptoms. It is positively but weakly correlated with temperature, hyperinflation, antibiotic usage and supplemental oxygen administration. It is subject to substantial interobserver variability.

Acute Disease↗

PubMed1993

An audit of comparative views in elbow trauma in children.

A comparative radiograph of the contralateral elbow was obtained in only 30 (2.5%) of children examined after elbow trauma. Interpretation by junior clinical staff was changed in only three children (0.25%). Radiological review of the ipsilateral elbow alone altered diagnosis in six (20%) of the 30 children referred for comparative views and agreed with the final clinical diagnosis in 29 (97%). Comparative views were requested by inexperienced clinical staff in 28 (95%) of cases and were unnecessary in all patients. A senior radiological or clinical opinion would have resolved problems at interpretation.

Elbow Joint↗

PubMed1992

The importance of clinical details when reporting accident and emergency radiographs.

The effect of clinical information on the accuracy of reporting accident and emergency (A&E) radiographs was studied in two A&E officers and five radiologists involved in their daily reporting. Each was shown 50 sets of radiographs, 30 subtle fractures and 20 controls. In one half the clinical history and precise localization was provided, and in the other half no such information was given. After an interval of 6 months the radiographs were viewed again with the amount of information reversed. The observers were asked to determine the presence of injury, describe its site, and indicate how sure they were of their diagnosis. Correct diagnosis was improved from 72.3 per cent to 80.3 per cent overall, and from 68.1 per cent to 81.4 per cent in the fracture group. All observers improved their performance with clinical details. The results confirm that accurate clinical details improve injury location.

Accidents↗

PubMed1986

Genetic analysis of malformations causing perinatal mortality.

An analysis of congenital malformations, other than neural tube defects, which have contributed to perinatal mortality in Leicestershire is presented for the years 1976 to 1982 inclusive. Chromosomal, single gene, or polygenic inheritance accounted for 67% of cases.

Chromosome Aberrations↗

PubMed1985

High incidence of Meckel's syndrome in Gujarati Indians.

Five probable cases of Meckel's syndrome have been ascertained retrospectively through the Leicestershire Perinatal Mortality Survey for the years 1976 to 1982. All of these babies were born to Hindu parents originating from the Gujarat State in India, suggesting that Meckel's syndrome is particularly common among this ethnic group, with a gene frequency of approximately 0.028.

Abnormalities, Multiple↗