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Biomedical subjects

A Baert

Publications and source records attributed to A Baert.

At least 19 recordsLinked to original sources
PubMed2006

[Case of death occurred after an injection of aetoxisclerol. The responsibility of the product should be discussed].

A 35-year-old woman has suffered from faintness with cardiovascular failure at the end of a sclerotherapy session for varix management. The injected product was Aeloxisclerol (DCI lauromacrogal 400). The death came up very quickly. The autopsy didn't reveal any traumatic lesion. The anaphylactic choc could be ruled out. Macroscopically, the heart showed a right ventricular dilatation. The toxicological analysis didn't reveal any medicinal substances. Histology showed the presence of lipid degeneration of all the right-ventricle wall The discussion is carried out on the role played by this previous health-state on the onset of death, and also on the incidence of sclerotherapy using this product. and the onset of death. We are carrying out this discussion by taking in mind the nature of the product injected and the information available in the literature concerning the lipid degeneration of cardiac muscle. Quickly after this case, the AFSSAPS (The French Agency for Sanitary Security of Health Products) has emitted an written alert which correlates with the requirements of principles of precaution although it is not founded on the totality of investigation results done for this medicolegal case.

Adult↗
PubMed2001

An ex vivo study on radiofrequency tissue ablation: increased lesion size by using an "expandable-wet" electrode.

The present comparative study was conducted to validate a newly developed "expandable-wet" electrode for an increased lesion size of radiofrequency ablation (RFA) on excised beef liver. The expandable-wet electrode, which allows interstitial hypertonic saline infusion through retractable curved needles, was compared with "expanded-dry" and "unexpanded-wet" electrodes for RFA lesion size and other parameters. A total of 120 lesions were created under 50 W (groups A-C) and 90 W (groups A'-C') power control mode for 10 min at each ablation site with the following groups: group A and A' of expanded-dry electrode (needles deployed but saline uninfused); group B and B' of unexpanded-wet electrode (saline infused but needle undeployed); and group C and C' of expanded-wet electrode (needles deployed and saline infused). Together with lower impedance and higher power output, the lesion size in group C (5.3+/-0.4 cm) and C' (6.0+/-1.0 cm) were significantly larger (P<0.01) than that in group A (3.3+/-0.3 cm) and A' (2.0+/-0.2 cm), and group B (3.8+/-1.0 cm) and B' (2.6+/-0.4 cm). The RFA lesion size can be significantly enlarged when the expandable electrode is complemented with interstitial hypertonic saline infusion. This design may improve the efficacy of RF tumor ablation.

Animals↗
PubMed2000

Fatal aluminum phosphide poisoning.

A 39-year-old man committed suicide by ingestion of aluminum phosphide, a potent mole pesticide, which was available at the victim's workplace. The judicial authority ordered an autopsy, which ruled out any other cause of death. The victim was discovered 10 days after the ingestion of the pesticide. When aluminum phosphide comes into contact with humidity, it releases large quantities of hydrogen phosphine (PH3), a very toxic gas. Macroscopic examination during the autopsy revealed a very important asphyxia syndrome with major visceral congestion. Blood, urine, liver, kidney, adrenal, and heart samples were analyzed. Phosphine gas was absent in the blood and urine but present in the brain (94 mL/g), the liver (24 mL/g), and the kidneys (41 mL/g). High levels of phosphorus were found in the blood (76.3 mg/L) and liver (8.22 mg/g). Aluminum concentrations were very high in the blood (1.54 mg/L), brain (36 microg/g), and liver (75 microg/g) compared to the usual published values. Microscopic examination revealed congestion of all the organs studied and obvious asphyxia lesions in the pulmonary parenchyma. All these results confirmed a diagnosis of poisoning by aluminum phosphide. This report points out that this type of poisoning is rare and that hydrogen phosphine is very toxic. The phosphorus and aluminum concentrations observed and their distribution in the different viscera are discussed in relation to data in the literature.

Adult↗
PubMed1996

Spiral CT of intracranial aneurysms: correlation with digital subtraction and magnetic resonance angiography.

Spiral CT and magnetic resonance angiography (MRA) were performed in ten patients with 14 intracranial aneurysms known from conventional angiography. All lesions, the smallest 3 mm in diameter, were visible on spiral CT and MRA. The neck of the aneurysm and its anatomical relations could very accurately be determined in all cases. Advantages of spiral CT over MRA are: a short acquisition time with reduction of motion artefacts, no dependence on flow rate or cardiac output, and excellent visualisation of calcification, thrombus and bony landmarks. Disadvantages are the necessity for iodinated contrast medium, long postprocessing and reconstruction time and the possibility of overlap of bone and venous blood.

Aged↗
PubMed1994

Iatrogenic spinal epidermoid tumour associated with tuberous sclerosis. A diagnostic pitfall.

We present a case of spinal epidermoid tumour that was probably caused by lumbar punctures. The tumour was detected on MRI in a child with tuberous sclerosis complaining of atypical low back pain. Preoperatively the tumour was considered to be a cystic astrocytoma of ependymoma of the conus terminalis. The association of tuberous sclerosis with a spinal tumour is rare but has been recorded in the literature. The diagnosis was an epidermoid tumour (E.T.). The MRI appearances were unusual for a spinal ET: the signal intensity changes were different from those reported in the literature and the presence of calcification and cavitation has not yet been reported. This case represents a diagnostic pitfall, since both entities were unrelated.

Child↗
PubMed1991

Cholesteatomas of the temporal bone: a comparison of CT and operative findings.

In a series of 45 consecutive cases with proven cholesteatoma, the correlation between the preoperative CT findings and observations made at surgery was evaluated. On the preoperative CT protocol 11 parameters of the anatomical and pathological features of the temporal bone were correlated with the operation report. Except for the ossicles, a high degree of correlation was noted between CT findings and those at the operation.

Adolescent↗
PubMed1989

Uneven lipomatosis: a pitfall in pancreatic sonography.

A marked difference in echogenicity between the anterior and posterior parts of the pancreatic head was demonstrated by pancreatic ultrasound in 4 patients. This finding could not be related to local pancreatic or peripancreatic pathology. In all patients the dorsal portion of the head, including the uncinate process, appeared less echogenic than the ventral part of the head, body, and tail. The level of demarcation was identical in all 4 cases, coinciding with the expected fusion line of the embryological dorsal and ventral pancreatic origin. Pathology available in 1 patient showed an uneven lipomatosis as an explanation for this hitherto unreported observation.

Aged↗
PubMed1989

The glossopharyngeal neurinoma. Case reports and literature review.

Glossopharyngeal neurinomas are rare entities. Only 16 cases have been described so far in the literature. Our experience with 2 cases demonstrates the non-specific and discrete clinical presentation of the ninth nerve neurinoma, but illustrates also some typical radiological aspects, enabling a more precise preoperative diagnosis. Two cases are presented and a survey of the literature is given.

Adult↗
PubMed1988

Surface coil magnetic resonance imaging of the orbit at 1.5T.

MRI of the orbit at 1.5-Tesla was performed in 5 healthy volunteers and 30 patients with a variety of pathological intraocular or intraconal conditions. Major advantages of MRI over CT include higher spatial resolution, higher tissue contrast, possibility of direct multiplanar imaging, absence of bony and dental artifacts, and of ionising radiation. Specific indications of MRI in orbital pathology concern differentiation of uveal melanoma from subretinal haemorrhage, identification of lesions of the orbital apex, the orbital fissure or the optic canal, differentiation of inflammatory pseudotumour from malignant lesions, determination of the posterior extension of lesions of the optic nerve, and detection of abnormal flow in normal or hypertrophic intraorbital vessels. Limitations are due to motion artifacts on T2 weighted sequences, less accurate visualisation of calcification, poor specificity of some findings, and absence of signal from cortical bone.

Cranial Nerve Neoplasms↗
PubMed1988

Blood pressure during long-term converting-enzyme inhibition predicts the curability of renovascular hypertension by angioplasty.

Percutaneous transluminal renal angioplasty (PTRA) was performed in 28 hypertensive patients with 50% or more unilateral renal artery stenosis. Prospectively, the study compared the extent to which systolic (SBP) and diastolic (DBP) pressure during long-term converting-enzyme inhibition (CEI) and the ipsi- to contralateral renal vein renin ratio (RVR) predicted success of PTRA, defined as SBP less than 160 mmHg and DBP less than 95 mmHg. Both SBP and DBP after PTRA were positively correlated with pressure during CEI (P less than 0.001) and negatively with RVR (P less than 0.03). In multiple regression these associations were independent and remained statistically significant. In discriminant analysis, a SBP during CEI less than 160 mmHg, a DBP during CEI less than 95 mmHg, and a RVR greater than or equal to 1.5 identified with equal accuracy the success of PTRA. Furthermore, in patients with a SBP during CEI less than 160 mmHg, the demonstration of a RVR greater than or equal to 1.5 increased (P less than 0.05) the prediction of a positive outcome from 50 to 67%. In contrast, in 92% of the patients with a SBP during CEI greater than 160 mmHg, PTRA was not successful. Thus, blood pressure measurements during long-term CEI predict the curability by PTRA of renovascular hypertension and can be employed either alone or in association with the RVR.

Angioplasty, Balloon↗
PubMed1988

Staging and follow-up of rheumatoid arthritis of the knee. Comparison of sonography, thermography, and clinical assessment.

Twenty patients with longstanding polyarticular rheumatoid arthritis (including knee involvement) were selected for this study. The severity of the knee synovitis was assessed before and during treatment (with intra-articular corticosteroid injections) using clinical scores, sonography, and thermography. In all patients, the inflammation regressed during treatment. During follow-up, the quantity of synovial fluid, as measured sonographically 10 days after the start of therapy, correlated best with the clinical status. Maximal regression of synovial thickening was noted on delayed sonograms performed three months after treatment. Thermographic peak temperature showed good correlation with the clinical status, but the thermographic index was unreliable.

Adrenal Cortex Hormones↗
PubMed1988

[Tracheobronchial stenosis of the premature infant. Treatment by balloon dilatation].

The case of a 30th week preterm newborn infant, ventilated because of hyaline membrane disease and presenting with localized stenoses of the carina involving both main-stem bronchi is described. The diagnosis was made on bronchoscopy and bronchography after a period of recurrent atelectases and lobar emphysema. Due to severe broncho-pulmonary dysplasia, surgical reconstruction was impossible. A balloon dilatation was successfully performed while the infant was still ventilated. He died however at the age of 180 days.

Bronchial Diseases↗