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A Bagni

Publications and source records attributed to A Bagni.

40 records · Page 3Linked to original sources
PubMedDate not supplied

[Clear cell sarcoma of the hand. Description of a case].

Clear cell sarcoma of the hand. Case report. Histologic, ultrastructural and immunohistochemical features of a case of clear cell sarcoma (also called malignant melanoma of soft parts) arisen in the index finger of the right hand in a 28 year-old-woman are described in this report. Typical forms of this tumor are deeply located and associated with tendons and aponeuroses, lacking cutaneous involvement. The tumor has to be differentiated from other benign and malignant lesions of the soft parts, such as a giant cell tumor of tendon sheaths and a fibrosarcoma. The demonstration of melanin and a positive immunohistochemical reaction for S-100 protein and HMB-45 (a melanin-associated antigen) can assist in the differential diagnosis. In spite of a slow and protracted clinical course, many of the patients experience multiple local recurrences and distant metastases. Prognosis is poor in a high percentage of cases.

Adult↗
PubMedDate not supplied

Immunocytochemical detection of estrogen receptors by staining with monoclonal antibodies on cytologic specimens of human breast cancer.

A study was undertaken to test the possibility of determining the estrogen receptor (ER) content in human breast cancers by staining with commercial specific monoclonal antibodies (MAbs) on cytologic specimens (touch imprints and fine needle aspirates). The aspirates were suspended in a cell culture medium and cytocentrifuged onto slides to preserve their morphologic characteristics and to allow a proper immunocytochemical staining for ERs. MAb staining for ER was also performed on the respective surgical samples. The staining of cytologic samples for ER showed 100% specificity and 95% sensitivity in comparison to the staining of the histologic samples. Moreover, comparison of the percentage of stained cells in the cytologic specimens to the ER content in the respective surgical specimens, as assayed by the dextran-coated charcoal method, showed the MAb staining of cytologic samples to have 94% specificity and 100% sensitivity. These results support the reliability of MAb staining for ERs in cytologic samples and suggest that it could be the assay of choice in particular clinical settings in the evaluation of primary and recurrent breast cancers.

Antibodies, Monoclonal↗
PubMedDate not supplied

Adult celiac disease and primary sclerosing cholangitis: two case reports.

The association of primary sclerosing cholangitis and celiac disease is uncommon. Herein, we report on 2 different cases which developed this association. Case 1 was a 59 year-old female who firstly complained of symptoms of cholestasis. The diagnosis of primary cholangitis was made on liver biopsy, and the endoscopic retrograde cholangiopancreatography (ERCP) showed narrowing and irregularity of the extra- and intrahepatic bile ducts. The results were positive for antiendomysial antibodies and the jejunal biopsy confirmed the coexistence of celiac disease, which was asymptomatic until that moment. The gluten-free diet ameliorated the index of cholestasis. Case 2 was an old man suffering from undiagnosed celiac disease for at least 5 years prior to admission at our Department. The diagnosis was based on the histological examination of a jejunal biopsy. The patient did not follow the gluten-free diet and was again admitted to our Department 6 years later with symptoms of cholestasis. The liver biopsy and ERCP confirmed the diagnosis of primary sclerosing cholangitis.

Adult↗