Biomedical subjects
Publications and source records attributed to A Barigazzi.
The Authors report their experience concerning 237 stapled sutures performed during 93 gastro-intestinal operations. Intraoperative technical advantages are described and improved postoperative courses are outlined; in particular earlier recovery of intestinal function, minimal rate of complications and 11-day average post-operative stay are reported.
Ten patients had their large bowel continuity restored (5 after Hartmann resection and 5 after defunctioning left colostomy) by an improved, essentially aseptic, stapling technique with the premium CEEA stapler. There were no deaths and no complications.
The Authors report their experience about diaphragm traumatic herniae. After showing the general problematics, they study 11 cases they had the opportunity to observe: 7 acute and 4 chronic herniae, and appraise the diagnostic and therapeutical peculiarities of such pathology.
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The authors after giving a general view of retroperitoneal tumors also describe briefly their anatomo-clinical features pointing out the controveries of these neoplasms. Personal case histories are illustrated emphasizing the importance of shortening the time of diagnosis in regards with already sintomatic neoplasms which are misdiagnosed. The efficiency of present methods of diagnosis in relation with therapeutic problems is documentated and acknowledged.
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More than by a practical viewpoint, the experimental graft of stomach is very useful like model for the study of gastrointestinal physiopathology. Starting from these considerations the AA. have set up a new method for the execution of stomach heterotopic homograft in rat and they have studied the secretory activity without immuno-suppressed therapy. Not inbred rats have been used; their middle survival has been of 9,3 days. The secretion has been regular up to 5th-6th day; in the same time the AA. have made histopathologic studies on the transplanted stomachs of animals that had been sacrificed at programmed intervals of time, which have outlined the progressive growth of a reaction of intense immunological rejection.
The principal aim of this study is to set up a new microsurgical technique that can be reproducible easily for the execution of orthotopic homograft of stomach in rat. The vascularization of homograft is given, for arterial district by a termino-terminal anastomosis between celiac artery of donor and right renal artery of receiving, and, for venous district, by a termino-lateral anastomosis between portal vein of donor and vena cava of receiving. The middle survival of rats that were had a graft, in this first stage of research, has been of 3 days, therefore it hasn't't been possible to look into the function of graft.
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In examining some procedures of general evaluation of the operative risk the Authors direct their attention to the performance of cell-mediate reactivity skin tests and consider a set of 42 patients (of whom 11 as controls, and 31 "high risk"). The results obtained are interesting and evidence the high reliability of these tests in evaluation of infective morbidity and mortality in neoplastic and non-neoplastic patients: in fact a negative response means high morbidity and mortality while a positive response corresponds to normal surgical healing. In tumoral patients, moreover a relationship between skin tests and clinical stage of the disease is observed: negativity of the test means a terminal stage and hence absolute inoperability: positivity corresponds to an advanced stage and hence relative operability (exploratory laparatomy and thoracotomy). The Authors conclude by stressing that the tests have a practical utility and prognostic value higher than those of other methods.
The AA. intend to study the healing process of digestive sutures in dog that have been made with mechanical instruments that have metal agraphes. The used instruments are the American models of United Surgical Corporation in New York that have: --LDS pliers; --GIA pliers; --TA mod 90, 55, 30, pliers. They had made 15 operations of digestive surgery: gastric resections sec. Billroth II, anastomoses of ileum, colic anastomoses. In total they have made 45 sutures. After an established period the same animals were operated on again for controlling the results of made operations and the macro and microscopic evolution of sutures. The study of healing has shown a quick and exact repairing process for first intent, different from sutures that are made manually with threads that, notoriously, develop slowly for second intent.
The Authors present 38 cases of surgical revascularization for arteriosclerosis obliterans of the lower extremities, operated in Clinica Chirurgica of Ancona during the space of three Years, from 1974-1977. The morphological profile of the sphygmic wave and pressures of occlusion or Travis Winsor's index were studied pre and postoperatively with Doppler ultrasonic flowmeter. The patency of vascular grafts and after thromboendarterectomy was shown by T.W.'s index. With this method, besides establishing a program for postoperative arteriography, a lesser use of the latter was shown.