Biomedical subjects
Publications and source records attributed to A Barlattani.
We report a case of Budd Chiari syndrome with clinical onset during post partum in a patient with SLE. Etiopathogenetic correlations between pregnancy and BDS and between SLE and BDS are discussed, with particular regard to lupus anticoagulant factor. Furthermore, the diagnostic role of abdominal CT is emphasized.
We report a case of venocclusive (VOD) disease secondary to inhalation of an insecticide. Pathological features of liver injury are illustrated with regard to patchy lesions shown by a new computer assisted colorimetric method. A possible role of immuno-complexes in the development of endothelium damage to centro-lobular veins is discussed.
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PMF represents today the best solution for the functional rescue of a tooth cured by endodontics. After a careful analysis of the international literature the Authors in this study examined the resistance of four different kinds of PMF under laboratory conditions, applying external pressure to them until a steady rise in lateral direction caused a fracture in the specimens under study. On the basis of the results obtained, the Authors deducted that among different models tested, traditional long modified PMF is the most adapt for tolerating load of compression to preserve the integrity of the dental residual structures.
Retraction of gingival margin means a very important step to take a precise impression. Most used methods are electrosurgery and retraction's fibres. This study compares both techniques analysing the reaction of gingival tissues by anatomical-histological observation.
Primary cultures of human gingival fibroblasts from patients of different age have been established. Histotype characterization has been confirmed by ultrastructural morphology and by the positivity of intermediate filament vimentin. Extracellular matrix expression has been analyzed by immunocitochemistry. Our data demonstrate that the extracellular matrix of human gingival fibroblasts is composed of type IV collagen, other than fibronectin and type I-III collagens.
The Authors wanted to establish which could be for every impression material tested, the most favourable moment for the development of plaster models in a steady environment conditions of temperature and relative humidity. From the analysis of the results obtained, we can clearly conclude that every material examined offers an ideal time interval in which we have to cast the model in plaster. This study aspires to be an invitation to all operator in the sector, to repeat this experience in their work environment to know and better manage the procedures and the materials used, from the taking the impression to the executing of the plaster model.
This study, starting from the revision of traditional anatomy proposed to value TMJ and its components through dissection of human TMJ, and especially to examine the anatomic function of the lateral pterygoid muscle. Twenty dissections of left human TMJ were made. Every block was fixed in solution of 10% of formalin and dissections were made to show every components of articulation. Further thin sections were made for histological examination. The purpose of the study was to evaluate the lateral pterygoid muscle as a single unit compared to the function.
The purpose of this study was to examine and compare, in the same experimental conditions, the effects and the behaviour of two different materials, using them for cementation of a prosthetic reconstruction: a cianoacrilic compound (B20 cianoacrilate 3M); a traditional cement of zinc phosphate (Harvard Cement). The comparative study with the optical microscope between butilcianoacrilate and traditional cement has shown minimum levels of marginal discrepancy for both materials examinated (about 13 microns). The high resistance of cianoacrilate to traction, compared with the other fixing cement, makes us conclude this study in the hope that further research could confirm and introduce this materials in the practice of prosthetic dentistry.
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A case is described, that came to our attention for suspected acute intermittent porphyria, with abdominal pain and ascending tetraplegia. The patient (HIV positive and with a HBsAg positive chronic aggressive hepatitis) was a heroin addict. In urine: high porphyrins with extremely increased delta amino-levulinic acid (ALA) and normal porphobilinogen. High protoporphyrin was present in blood red cells. The lead poisoning was confirmed by a very low ALA-dehydratase activity in erythrocytes and a high content of lead in urine and plasma. With Ca-versenate and penicillamine the abdominal and neurological symptoms rapidly disappeared. The possibility of contact with lead, professional or environmental, was ruled out. It was found however, that shortly before the appearance of symptoms, the patient had used a batch of unrefined brown sugar heroin, which was probably mixed with lead salts. It is noteworthy that during the same period, other young heroin addicts died with similar symptoms.
A multicenter double-blind clinical trial was undertaken to evaluate the efficacy of a short-term somatostatin treatment versus a short-term vasopressin treatment on acute hemorrhage from esophageal varices in patients with liver cirrhosis and portal hypertension. Forty-nine patients with massive hemorrhage and endoscopic diagnosis of bleeding esophageal varices completed the study. Patients were randomly assigned to somatostatin treatment (24 patients: 250 micrograms/hr i.v. for 48 hrs) or vasopressin treatment (25 patients: 0.1 U/min i.v. for 48 hrs). The Sengstaken-Blakemore tube was utilized, when needed, for a six hour period. In case of failure the patients were crossed-over to the other treatment. Patients in whom the bleeding stopped at 48 hrs, were randomly assigned to somatostatin (250 micrograms/hr i.v.) or placebo for seven days. Bleeding stopped in 68% of patients treated with somatostatin and in 28% of patients treated with vasopressin (p less than 0.0013). Mortality rate was lower, but not significantly so, in the somatostatin group compared to the vasopressin group. No differences were noted between somatostatin and placebo in preventing bleeding recurrences. These data suggest that somatostatin, when combined if necessary with a 6 hour period of balloon tamponade, is more effective than vasopressin at low doses in controlling severe hemorrhage from esophageal varices in patients with liver cirrhosis and portal hypertension. A clinical use of somatostatin seems to be indicated in these patients.
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Considering liver cirrhosis a limit model, and therefore a condition suitable for the analysis of changes of lipid metabolism in liver disorders generally, the authors examined the L-CAT pattern, total and free cholesterol, HDL-cholesterol and APO-A in sixty-five subjects; fifty-three were suffering from liver cirrhosis, and were subdivided into those who were diabetic in addition, and those who were not, as well as according to the severity and duration of the liver disease; the remaining twelve were healthy controls. Analysis of the findings showed L-CAT to diminish significantly as the metabolic changes due to liver injury worsen. Contrary to the other parameters studied, L-CAT was the only one for which significant changes were found on analysis of variance comparing non-diabetic cirrhotics of varying severity. Further comparison suggested the idea that the reduction of L-CAT activity was correlated to the rate of progression of the disease rather than to the temporary condition of compensation or decompensation, so much so as to suggest itself as a valid parameter for the prognosis of liver cirrhosis.
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