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Biomedical subjects

A Bas Bernal

Publications and source records attributed to A Bas Bernal.

5 recordsLinked to original sources

[Complication associated with celiac disease].

Enteropathy associated T cell lymphoma is the most serious complication of celiac sprue. The incidence of malignancy, in general, is approximately twofold greater in celiac disease than in the general population, but the risk of specific gastrointestinal malignancies is markedly increased. Lymphoma of the small intestine, comprises approximately 50% of the malignancies, and the most are of T-cell origin. We report a case of celiac disease associated T-cell Lymphoma of the jejunum in a woman. At the age of 33 the diagnosis of Celiac sprue was made, after institution of a gluten free diet the patient improved, but, fifteen year later, the patient begin with fever and abdominal pain. Laparotomy showed a perforation of the intestine by a tumour.

Celiac Disease↗

Ultrasound-guided fine-needle aspiration biopsy. Study of the cost per patient and comparison with computed tomography-guided biopsy.

Between February 1992 and July 1995, we performed 222 ultrasound-guided fine-needle aspiration biopsies (FNAB) in abdominal space-occupying lesions. The sensitivity was 90% and the specificity, 100%, with an overall diagnostic precision of 93%. We also determined the cost of each procedure (2,550 pesetas) and compared it with the cost of computerized tomography (CT)-guided biopsy (22,500 pesetas). These results and those reported in the literature indicate that there is no significant difference with respect to diagnostic yield, but that the difference in terms of expense is considerable. We believe that, in the assessment of abdominal lesions. CT-guided FNAB should be reserved for those lesions that prove inaccessible to ultrasound.

Adult↗

Malignant rhabdoid tumor of soft tissues: a cytopathological and immunohistochemical study.

We describe the cytopathological and immunohistochemical features of a primary malignant rhabdoid tumor (MRT) located in the left forehead region of an 8-mo-old female. The cardinal characteristics are hyaline cytoplasmic inclusions, rounded or bean-shaped nucleus, vesicular chromatin, central prominent nucleolus, and poorly defined cytoplasmic profile. Both the cytoplasm and the hyaline inclusion are vimentin and keratin positive, but negative with desmin, S-100 protein, neuron-specific enolase, (NSE) myoglobin, leukocyte common antigen (LCA), and alpha-1-antichymotrypsin. This immunohistochemical pattern, although not exclusive to MRT, is fairly typical of MRT, and when it is assessed in conjunction with cytopathological findings and clinical data permits a confident diagnosis of MRT. We emphasize the utility of immunohistochemical techniques in making the differential diagnosis of MRT against other childhood round-cell tumors.

Biopsy, Needle↗

Diagnosis of collagenous spherulosis of the breast by fine needle aspiration cytology. A report of two cases.

We describe the cytopathologic features of two cases of collagenous spherulosis of the breast on fine needle aspiration cytology. The main findings were a moderately rich cellular aspirate, monolayered epithelial clusters with bland nuclei, naked bipolar nuclei and light green (Papanicolaou stain) or pink (Diff-Quik) spherules surrounded by a ring of comma-shaped nuclei resembling myoepithelial cells, located either at the heart of the epithelial clusters or detached from them. We also comment on the differential diagnosis with adenoid cystic carcinoma of the breast, signet-ring carcinoma and myospherulosis.

Adult↗