[Procedures for beginning antituberculosis treatment].
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Biomedical subjects
Publications and source records attributed to A Basacopol.
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Berodual (Duovent) was tested in 40 bronchial asthma patients in comparison with a similar group treated with fenoterol. The results of FEV1.0 investigation showed no significant differences: increases of 15% were noted in both groups. In two other groups (40 bronchial asthma cases each) treated with berodual and Atrovent, respectively FEV1.0 values were significantly different: increased by 5% in the Atrovent group, and by 15% in the berodual one. Berodual showed the advantage of inducing the same strong bronchodilation of similar duration, though applied in doses by far smaller than fenoterol or Atrovent. A diminution of the clinical evolution score from 3 to 0.7, an increase by 15%; in FEV1.0, and no changes as regards the immunological tests (IgA, IgG, IgM, Clq, C3) were obtained in the group treated with berodual for 4 weeks.
Sera from 67 tuberculosis patients and 30 healthy subjects have been analyzed for the presence of specific antibodies against polysaccharide, protein and glycolipid antigens from H37Rv strain of Mycobacterium tuberculosis. The results proved the advantages of using the glycolipid antigens in diagnosing tuberculosis as well as the relationship between the antibodies level and the extension of the pulmonary tuberculous lesions.
The active bronchodilators and anti-inflammatory drugs used as dry powder in inhalatory treatment of bronchial asthma represent an important advance during last years. In this way the inconveniences of pressurized aerosols treatment where the drugs are only partially inhaled as well as severe side-effects of systemic corticotherapy are avoided. The bronchodilator drug Ventodisk and the antiinflammatory Becodisks as dry powder are given by inhalation with a special device (Diskhaler). The study deals with a group of 60 subjects with moderate and severe forms of bronchial asthma out of which 20 were treated by Ventodisk associated to Becodisks and other two groups of 20 subjects each treated during the same interval time with only Becodisks and Ventodisk respectively. The clinical results after two months treatment were much better in the first group of subjects (85% good results) in comparison to Becodisks (75%) and Ventodisk (60%) treated cases. One can state in conclusion that the association of Ventodisk to Becodisks leads to very good results in basic treatment of bronchial asthma.