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Biomedical subjects

A Bava

Publications and source records attributed to A Bava.

At least 19 recordsLinked to original sources

Opposite musical-manual interference in young vs expert musicians.

Cerebral lateralization for music has been studied through a music-manual interference paradigm (tapping) in a group of young musicians (seven males and seven females) attending the 1st and 3rd intermediate grades of Udine's "J. Tomadini" State Conservatory of Music and in a group of graduated expert musicians or higher course students during the execution of three distinct tasks (singing notes, whistling a melody and singing a melody). A significant superiority of the right hemisphere (greater degree of interference with the left hand) in these tasks has been found in young musicians, while an opposite left hemisphere superiority (greater degree of interference with the right hand) was evident in the expert musicians. Other differences between sexes and tasks were not significant. The modification of hemispheric specialization occurring during academical musical training are discussed in terms of the role of education in the cerebral organization of superior cognitive functions.

Adolescent

Cerebral lateralization in simultaneous interpretation.

Cerebral asymmetries for L1 (Italian), L2 (English), and L3 (French, German, Spanish, or Russian) were studied, by using a verbal-manual interference paradigm, in a group of Italian right-handed polyglot female students at the Scuola Superiore di Lingue Moderne per Interpreti e Traduttori (SSLM-School for Interpreters and Translators) of the University of Trieste and in a control group of right-handed monolingual female students at the Medical School of the University of Trieste. In an automatic speech production task no significant cerebral lateralization was found for the mother tongue (L1) either in the interpreting students or in the control group; the interpreting students were not significantly lateralized for the third language (L3), while weak left hemispheric lateralization was shown for L2. A significantly higher degree of verbal-manual interference was found for L1 than for L2 and L3. A significantly higher disruption rate occurred in the meaning-based mode of simultaneous interpretation (from L2 into L1 and vice versa) than in the word-for-word mode (from L2 into L1 and vice versa). No significant overall or hemispheric differences were found during simultaneous interpretation from L1 into L2 or from L2 into L1.

Adult

Electrophysiologic properties and nature of ventrolateral thalamic nucleus neurons reactive to converging inputs of paleo- and neocerebellar origin.

Acute experiments were carried out in chloralose-anesthetized, curarized, and artificially ventilated cats to investigate the consistency and functional characteristics of converging cerebellar nuclear (fastigial, interpositus, dentate nuclei) inputs to single neurons of the ventrolateral thalamic nucleus, and the nature (thalamocortical relay or interneuronal) of its convergent neuronal population responsive to stimulation of the cerebellar nuclei. From unitary analysis of both extra- and juxtacellular recordings, we conclude that convergence of paleo- and neocerebellar impulses on thalamic ventrolateral neurons occurs widely, and that both excitatory (mono- and polysynaptic) and inhibitory (di- and polysynaptic) effects are induced on the same neurons by cerebellar nuclei stimulation; these effects concern about 40% of the thalamic ventrolateral neuronal population tested using the extracellular recording technique and about 75% of the ventrolateral nucleus neurons tested using the juxtacellular recording; activation of neocerebellar nuclear outputs generates mainly excitatory and excitatory-inhibitory response patterns, whereas activation of the paleocerebellar nuclear outputs evokes predominantly inhibitory and excitatory-inhibitory response patterns; the convergent paleo- neocerebellar neurons are found commonly in the more anterior ventrolateral nucleus stereotaxic planes; and from the results obtained by stimulation of the somatomotor cortical areas, a large proportion of the ventrolateral nucleus convergent units consists of thalamocortical relay cells. The results have implications for a possible integration between posture and voluntary movements at the level of the thalamic relay nucleus of the cerebellar-cortical pathway, and an interaction between central feedback and peripheral feedback in the programming, execution, and correction of voluntary movements.

Animals

Fastigial unit activity during voluntary movement in primates.

To examine the proposition that fastigial n. of cerebellum provides a fast feedback pathway to suprasegmental structures for spinal information regarding movement. Macaca irus were trained to make flexion and/or extension voluntary wrist movements. Fastigial neuron activity was then correlated with force, velocity, handle position and with shoulder or forearm muscle activity. From 200 units (75% participating), our data establish that fastigial neurons are uniformly recruited after movement onset, processing force-velocity information. Units were found specifically correlated with force or velocity alone. Fastigial activity is strategically placed to provide a 'correction' signal path for motor performance.

Animals

[Convergence effects evoked in neurons of the thalamic ventrolateral (VL) nucleus by the stimulation of paleo- and neocerebellar nuclear efferents].

The functional characteristics of the cerebellar nuclear outputs (fastigial, F.; interpositus, I.; dentate, D. nuclei) convergence on single neurones of th ventrolateral (VL) thalamic nucleus were studied in chloralosed, curarized and artificially ventilated cats (pCO2 continuously monitored), by means of the usual electrophysiological stimulation and intracellular recording techniques. From the experimental results on 90 VL n. neurones, with the analysis of the evoked cerebellar nuclear outputs unitary responses, it is possible to conclude: a) 69% of the reactive VL n. units are convergence neurones (CN); b) 34% of the CN are reactive to stimulation of all three cerebellar nuclei, showing similar patterns, with predominantly excitatory effects when located in the dorso-medial VL n. region and opposite patterns (excitation and inhibition) when located in the ventro-lateral VL n. region; c) 30% of the CN are reactive to the F.n and I.n. stimulation, often with opposite patterns; d) 36% of the CN are reactive to the D.n.-F.n. and D.n.--I.n. stimulation, usually with similar patterns. From this evidence, the effects evoked by the D.n. stimulation on to VL n. neurones seem to potentiate the F.n. and I.n. actions, whereas teh convergent F.n.-I.n. inputs exert often opposite effects on the same neurone. The dorso-medial and the ventro--lateral VL n. regions also seem to receive different actions from the converging cerebellar nuclear outputs. All the results are functionally discussed in terms of a possible integration between posture and voluntary movements at the level of the thalamic relay nucleus of the cerebello-cortical pathway.

Animals

[Pre- and post-operative evaluation of biologic parameters in patients with scoliosis (author's transl)].

The authors had studied biological parameters of respiratory and muscle function in patients effected by scoliosis before and after surgical treatment according to Harrington method, in order to evaluate a correlation with the anatomical deviations. The study has been led by spirometric and electromyographic tests, which have show a real correspondence between the anatomical situation and the considered parameters before and after surgical treatment, and emphasizing an improvement of respiratory and muscle function.

Adult

[Mitotic activity in the glandular epithelium of the rat small intestine after electrothermocoagulation of the tubero-infundibular region of the hypothalamus and simultaneous resection of the pineal gland].

Radio-frequency lesions of the tubero-infundibular region of the hypothalamus and simultaneous pinealectomy are performed in rats. The double operation is followed by a significant increase of mitotic rate in the small intestine glandular epithelium. This increase is higher than the addition of the effects that are caused by each operation.

Animals

[The effects of lesions in several zones of the brain on cell multiplication in the glandular epithelium of the rat small intestine].

Radio-frequency lesions of tubero-infundibular region of the hypothalamus are followed by a significant increase of the mitotic rate in the small intestine glandular epithelium in rats. This increase does not occur when radio-frequency lesions are located in the anterior and posterior hypothalamus, in the dorsomedial thalamus and in the cerebral hemispheres.

Animals