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Biomedical subjects

A Beitzke

Publications and source records attributed to A Beitzke.

At least 55 records · Page 3Linked to original sources

[Percutaneous transluminal balloon valvuloplasty in the treatment of congenital valvular pulmonary stenoses in childhood].

Five children aged 2 to 6 years with isolated pulmonary valve stenosis underwent treatment by percutaneous transluminal balloon valvuloplasty. A peak systolic gradient between right ventricle and pulmonary artery (delta RV/PA) was reduced from 60.4 +/- 18.7 mm Hg to 21.7 +/- 12.6 mm Hg and the right ventricular pressure fell from 76.2 +/- 20.7 mm Hg to 43.0 +/- 16.4 mm Hg. There were no complications. Percutaneous transluminal balloon valvuloplasty is a safe method to treat isolated pulmonary valve stenosis. It benefits many patients over a long term period and may provide definitive treatment in some patients.

Angioplasty, Balloon↗

Mitral atresia with premature closure of the oval foramen, right-sided levoatriocardinal vein and thrombus formation in the left atrium.

We describe a 4-week-old baby with mitral atresia, hypoplastic left ventricle, ventricular septal defect, preductal coarctation and premature closure of the oval foramen whose only outlet from the left atrium was a stenosed right-sided levoatriocardinal vein and who in addition developed left atrial thrombi. Cross-sectional echocardiography was extremely helpful in establishing the diagnosis.

Abnormalities, Multiple↗

[Percutaneous balloon dilatation of pulmonary valve stenosis].

Balloon valvuloplasty was carried out on five children with isolated valvular pulmonary stenosis. One child had a residual stenosis following a Brock's transventricular valvotomy. The systolic gradient between the right ventricle and the pulmonary artery fell from 60.4 +/- 18.7 mmHg to 21.8 +/- 12.0 mmHg. Right ventricular pressure fell from 76.2 +/- 20.7 mmHg to 43.0 +/- 16.4 mmHg. Percutaneous balloon valvuloplasty has proved to be an effective method for the treatment of isolated valvular pulmonary stenosis.

Angiocardiography↗

Continuous arteriovenous haemofiltration in children with postoperative cardiac failure.

Six children with refractory heart failure were treated by continuous arteriovenous haemofiltration. The cause of the failure was postoperative fluid overload or low cardiac output with anuria or oliguria. This produced a mean (2 SD) negative fluid balance of 1.4 (0.6) ml/kg/h and reduced mean (2 SD) body weight from 4.7 (2.2) to 4.2 (2.3) kg over a period of 57.5 (31.1) hours. Central venous pressure fell significantly from 13.7 (3.1) to 7.7 (0.7) mm Hg while the mean (2 SD) arterial pressure increased significantly from 44.6 (5.5) to 52.6 (5.1) mm Hg. In three infants urine production resumed when normal blood volume had been achieved. The other three infants needed further haemofiltration because of prolonged renal failure. All but one was weaned from artificial ventilation and catecholamine treatment. No adverse haemodynamic effects were noted. One child need operation for a femoral artery thrombosis after 12 days of continuous arteriovenous haemofiltration.

Female↗

[Heart function in infants and small children, whose mothers required tocolysis with hexoprenaline sulfate (Gynipral)].

Cardiac function was investigated in 23 retrospectively selected children (mean age 15 months, range 2/12-3 4/12), whose mothers had undergone a successful course of tocolysis around the 31st week of pregnancy. Hexoprenaline sulfate (Gynipral) had been given at a mean cumulative dose of 51,103 micrograms over an average period of 13.8 days. The infants were born at term; cases with marked birth asphyxia, low birth weight or other perinatal problems possibly influencing cardiac performance were not included. The examination included a chest X-ray, ECG (all standard leads) and ultrasonography. There was no evidence of myocardial dysfunction which might have been the late result of untoward effects of the beta 2-mimetics given during the last trimester of pregnancy. All probands were normally developed: on cardiological examination an incidental systolic murmur was found in 2 infants and border-line cardiomegaly in another proband. ECG revealed a wandering pace-maker and occasional ventricular extrasystoles in one 3 month-old boy, which is not necessarily abnormal at this age. Two-dimensional echocardiography showed normal cardiac anatomy in all 23 probands. One-dimensional M-mode showed normal left ventricular function parameters. The slightly elevated myocardial contractility demonstrated by means of the M-mode was attributed to increased sympathetic tone in the non-sedated children.

Child, Preschool↗

Development of aortic aneurysms in familial supravalvar aortic stenosis.

In a male patient with supravalvar aortic stenosis (SAS) and peripheral pulmonary arterial stenoses, aortic aneurysms developed between his first and fourth years of life. He died five days after correction of SAS and resection of aneurysms. Histologic examination revealed disarrangement as well as severe degeneration of elastic fibers in the aortic wall. This tissue defect is probably inherited through an autosomal dominant mechanism. It may lead to aneurysm formation. Only one case of SAS with aortic aneurysm has been previously reported.

Aortic Aneurysm↗

Pseudo-widening of cranial sutures as a feature of long-term prostaglandin E1 therapy.

Disturbance of desmogenous ossification of the skull is an extremely rare complication of long-term prostaglandin treatment. This report describes a newborn with pulmonary atresia, ventricular septal defect and ductus-dependent pulmonary blood flow in whom administration of prostaglandin E1 (PGE1) over a period of 96 days produced uncommon clinical and radiologic findings.

Cranial Sutures↗

[Surgical treatment of the isolated form of interrupted aortic arch].

We report on a 14-years old boy with isolated interruption of the aortic arch (type B). By the use of extracorporal circulation complete relief could be achieved by interposing a large Dacron tube. Follow up restudy demonstrated a normotensive patient without residual gradient of the systemic blood pressure.

Adolescent↗

[Possibilities of 2-dimensional echocardiography in childhood. II. Possibilities for use].

Two-dimensional echocardiography has been shown to be equal, or even superior, to cardiac catheterization in the diagnosis of congenital heart disease. On the basis of clinical and non-invasive investigations alone many cardiac malformations can be diagnosed correctly and an operation carried out without previous catheterization. This paper reports our findings with cross-sectional echocardiography in common and rare cardiac malformations using standardized imaging planes and typical transducer locations.

Aortic Valve Stenosis↗

[Clonidine poisoning].

Accidental clonidine poisoning of infants has been more frequently observed during the last years. The early onset of sedation together with miosis, hypotension, bradycardia and sometimes respiratory depression should draw our attention to clonidine poisoning. Treatment of cardiac and circulatory symptoms with atropine sulfate, epinephrine chloride, dopamine hydrochloride and intravenous fluids should start early. Ventilatory support must be available for children in case of apnoe. We report our experience with the treatment of five infants.

Apnea↗

[Balloon atrioseptostomy in 2-dimensional echocardiography].

Two-dimensional echocardiography allows complete evaluation of transposition of the great arteries including additional malformations. Pressure recordings and oxymetry are without indicative value in sick and hypoxic neonates and cardiac catheterization is therefore merely therapeutic (balloon atrial septostomy). In addition balloon atrial septostomy can be performed under echocardiographic control only. This procedure saves time and costs, avoids the risks of X-ray exposure and angiocardiography and can safely be performed in the pediatric intensive care unit. Five newborn babies with transposition of the great arteries were treated with this method.

Cardiac Catheterization↗

Double outlet left ventricle with intact ventricular septum.

Two cases of double outlet left ventricle with intact ventricular septum are reported. Both patients presented with neonatal cyanosis and signs of right ventricular outflow tract obstruction. Both have hypoplastic right ventricles with suprasystemic pressures, pulmonary to mitral valve continuity and the aorta in left-sided position. These seem to be the second and third cases of the malformation to be described thus far.

Angiocardiography↗

CT diagnosis of thrombosis of dural sinuses in childhood.

This paper describes the CT findings in five cases of cerebral and cerebellar sinovenous occlusion. Characteristic CT findings are the visualisation of the thrombosed sinuses and veins, known as the "filled triangle" and the "cord sign" on the control scan, and the "empty triangle" with tentorial and gyral enhancement after contrast enhancement. The high incidence of thrombosed internal cerebral veins and superior cerebellar veins with sinus thrombosis in children is remarkable. CT with both control and contrast enhanced scans will probably provide the correct diagnosis in the majority of cases.

Child, Preschool↗

[Cross sectional echoencephalography in infants].

Importance of echoencephalography increased during development of neonatal intensive care. In addition to investigations in neonates 2-D-echoencephalography even during pregnancy and infancy can be used for detection of intracranial pathology. A standardized method of investigation and the knowledge of the pathology of the expected lesions are of fundamental importance. During neonatal period and infancy intraventricular and subdural hemorrhage, brain tumors, postinfection sequelae, hypoxic brain damage, alteration of intracranial perfusion and cerebral malformations can be detected.

Age Factors↗