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Biomedical subjects

A Beitzke

Publications and source records attributed to A Beitzke.

At least 91 records · Page 5Linked to original sources

Two-chambered right ventricle: simulating two-chambered left ventricle.

Two cases are described of a most unusual variant of two-chambered right ventricle. In both the ventricular septal defect was between the distal chamber of the right ventricle and the left ventricle. However the extensive dividing 'septum' between proximal and distal parts of the right ventricle converted the latter, haemodynamically, into part of the left ventricle. In the first case the distal chamber supported the aorta in the left anterior position, the pulmonary artery arising from the proximal part of the right ventricle. In the second the pulmonary artery arose from the distal chamber and the aorta from the proximal chamber. Though in both the ventriculoarterial connection was double outlet right ventricle, functionally there was arterial concordance in case 1 and discordance in case 2. A further disconcerting feature was the resemblance of the distal right ventricular chamber to the rudimentary chamber of a univentricular heart of left ventricular type.

Angiocardiography↗

[Prenatal diagnosis by ultrasound of a very large heart (author's transl)].

Ultrasound diagnosis enabled identification of a congenitally very large heart. Due to this finding, no obstetric intervention was performed despite a foetal emergency situation. Hence, unnecessary surgery was avoided. The principal signs enabling clarification of the case by ultrasound were a vena umbilicalis of 2 cm thickness and the highly dilated heart which occupied 75% of the cross-sectional area of the thorax, besides the clinical clues, hydramnion and hydrops fetus.

Adult↗

[Multifocal (chaotic) atrial tachycardia in infancy].

A newborn baby shows atrial tachycardia and gets into cardiac failure by atrial fibrillation at 12 weeks of age. With digoxin and chinidin spontaneous conversion to multifocal atrial tachycardia occurs. Treatment with additional propranolol leads to atrial fibrillation and paroxysmal atrial tachycardia with block. When chinidin was discontinued atrial flutter occurred. With a maintenance therapy with digoxin and chinidin the baby remained asymptomatic, and sinusrhythm occurred at 6 months of age. At 9 months chinidin was discontinued. At 14 months of age, the child is well and in sinusrhythm with a maintenance digoxin therapy. This seems to be the third described case of multifocal atrial tachycardia in infancy.

Anti-Arrhythmia Agents↗

[Mucocutaneous lymph node syndrome in Austria -- Report of four cases; one with cardiac arrest. First of two parts: clinical observations (author's transl)].

Since October 1978, four cases of mucocutaneous lymph node syndrome, a disease previously not yet described in our country were observed in our childrens hospital. This particular disease has been described quite frequently in Japan since 1967. It has a characteristic manifestation being mostly benign and self limited. In a few cases however acute cardiac arrest has been described. The first case we observed expired as a result of acute coronary infarction on the twentyfifth day of illness although clinical improvement had been previously noted. At post mortem examination the coronary arteries showed changes consistent with arteriitis. The following three cases presented the more typical benign course of this disease one of them with deformities of the coronary arteries. The clinical synopsis describes the above mentioned cases.

Adrenal Cortex Hormones↗

[Congenital atrial flutter with hydrops fetalis caused by tocolytic therapy (author's transl)].

A 31-year-old healthy woman received Ritodrine (Pre-Par) from the 26th week of gestation because of twin pregnancy. Three weeks before birth continous intravenous medication with the same drug was commenced because of premature uterine contractions. Five days later a heart rate of over 200/minute was noted in one of the twins. This tachycardia persisted until birth while the heart rate of the other twin remained normal. At 33 weeks monozygotic female twins were delivered after artifical rupture of membranes. One twin was normal, birth weight 1.6 kg. The other baby showed persistent atrial flutter, was hydropic (weight 2.75 kg) and suffered from gross cardiac failure. Atrial flutter was converted to sinus rhythm one hour after birth by DC-countershock. Digoxin was commenced, the child rapidly improved and now still remains in sinus rhythm six month later.

Atrial Flutter↗

[Indomethacin in IRDS with PDA phenomenon (author's transl)].

16 premature babies (all needing artificial ventilation, 15 suffering from idiopathic respiratory distress syndrome and one from severe apneic spells) received a single or double dose of indomethacin once the symptoms of an open ductus arteriosus further complicated their disease. Within 24 hours four patients showed closure of their duct, three other patients a very distinct improvement of their hemodynamic situation. There was no change of the ductus dependent symptoms in 8 other babies. One baby presented with a marked a worsening of its clinical situation and finally required surgical closure of its duct. There is quite a discrepancy found in the results reported from different centers. Starting from our results possible reasons for this discrepancy are discussed.

Apnea↗

[Persistent pulmonary hypertension in newborn infants (author's transl)].

Three cases of persistent pulmonary hypertension in newborn infants are reported. One patient developed this syndrome following a normal pregnancy and uneventful delivery, whilst the others had a history of fetal or perinatal distress. Cardiac catheterization showed pulmonary hypertension in two cases in the absence of cardiac or pulmonary disease or metabolic disorders; one of these babies died unexpectedly following initial improvement. The second infant died from massive cardiac failure before cardiac catheterization could be carried out. The surviving infant was reinvestigated at the age of 7 months and showed normal pulmonary pressure and no evidence of cardiac disease. Aetiology, haemodynamics and clinical picture of this syndrome are discussed in relation to the varying clinical features manifested by our patients and the course taken.

Cardiac Catheterization↗

[Arteriovenous aneurysm of the left internal thoracic artery with hypertrophy of the left upper limb (author's transl)].

Case report on a 5 years old boy suffering from a congenital arteriovenous fistula of the left internal thoracic artery. At the age of 9 months hypertrophy of the left arm combined with dilated veins in this area developed. Diagnosis was made by clinical examination together with a density in the left upper chest on x-ray and was confirmed by phlebography and thoracic aortography. A dilatation of the left heart, which was marked at the age of 9 months vanished in childhood without any therapy. The child was operated successfully.

Arm↗

[The hypertrophic obstructive cardiomyopathy (HOCM) of the newborn].

A case of a newborn infant with clinical and angiocardiographic signs of hypertrophic obstructive cardiomyopathy (HOCM) is presented. The baby died after a short therapy with beta-blockers. Light- and electron-microscopic investigations showed severe disorganization of muscular cellular arrangement and disturbances of intracellular structures of the interventricular septum. HOCM is a genetically determined disease which can present clinically in the newborn period and may simulate congenital cardiac malformations.

Adrenergic beta-Antagonists↗

[Results of nasotracheal intubation in acute epiglottitis (author's transl)].

20 of 34 patients with acute epiglottitis were treated with nasotracheal intubation. One patient died because of pneumonia, one patient was clinically dead when he arrived at hospital. After successful reanimation she died some hours later. All other patients left the hospital without any symptoms after an average stay of 12 days. The average duration of nasotracheal intubation was 39 hours. Nasotracheal intubation and adequate antibiotic therapy offer the most effective and secure approach to acute epiglottitis. A protocol for diagnostic and therapeutic regimen is presented.

Acute Disease↗

[Repetitive supraventricular tachycardia. Case report and electrophysiologic bases].

A typical case of repetitive supraventricular tachycardia is reported. Periods of normal heart rate are interrupted by short bursts of supraventricular tachycardia. In the case described this phenomenon can be explained by coexistence of reentry and an automatic rhythm from a subsidiary pacemaker. This pacemaker was found to be in the bundle of His; its automaticity showed a rate somewhat faster than that of the sinus node. Careful analysis of the surface electrocardiograms allowed a definition of the electrophysiologic events starting a run of tachycardia. The circus movement entertaining the tachycardia itself was found to result from AV nodal reentry.

Bundle of His↗

[Pulmonary hypertension after spontaneous closure of an atrial septal defect in infancy (author's transl)].

Clinical findings and haemodynamic data of an infant with atrial septal defect and hypoplasia of the left ventricle are reported. At the first cardiac catheterization at the age of 3 weeks an interatrial left to right shunt of 55% and a moderately elevated pulmonary artery pressure, but normal pulmonary vascular resistance were found. At repeat cardiac catheterization at the age of 6 month the atrial septal defect had closed spontaneously, however, the pressure in the pulmonary artery had risen to 90/55 mm Hg and pulmonary vascular resistance was elevated with 9.6 Um2. 3 months later pulmonary artery pressure had normalized to 35/15 mm Hg, but pulmonary vascular resistance was still elevated at 7.8 Um2.

Electrocardiography↗

[Transposition of the great arteries with horizontal interventricular septum (author's transl)].

Transposition of the great arteries with horizontal interventricular septum is characterized by a superior-inferior relationship of the ventricular chambers in the presence of ventriculo-arterial discordance. Embryologically this very peculiar anatomy can be explained by a rotation of the bulboventricular loop around a sagittal axis. A typical case is reported. The most important anatomical features are described and the embryologic mechanisms leading to this ventricular arrangement are discussed. The significance of this deformity to nomenclature of congenital heart disease is emphasized.

Angiocardiography↗

[Isolated right ventricular hypoplasia].

A 2-day-old female infant was presented with severe cyanosis without cardiac failure. The ECG revealed a normal axis and left ventricular hypertrophy. Chest X-ray examination showed a slightly but uncharacteristically enlarged heart. Cardiac catheterization and angiography showed isolated right ventricular hypoplasia with atrial septal defect. A large right to left shunt at atrial level produced marked systemic arterial desaturation. Up to the age of now nine months the patient remained in good health without cardiac failure. The clinical findings and surgical treatment of this rare malformation are discussed. Differential diagnosis with clinically similar malformations such as tricuspid atresia type 1 B or pulmonary atresia type 1 (with intact ventricular septum) is impossible without angiography.

Angiocardiography↗

Digoxin elimination by exchange transfusion.

The report covers four cases presenting simultaneous indications for digitalisation and exchange transfusions. Intravenous administration of digoxin was followed: 1. by monitoring of the behaviour of the plasma digoxin level; 2. by determination of the total amount of glycoside eliminated by the blood exchange. Particular attention was paid to the effect of the delay between injection and exchange transfusion on the amount of digoxin eliminated. All four cases showed moderate falls in plasma levels. The amounts of digoxin eliminated by exchange transfusion were in reverse relationship to the delay between administration of digoxin and the blood exchange. At no time did the eliminated fraction exceed 5% of the total amount present in the body.

Child, Preschool↗

[The syndrome of polysplenia (author's transl)].

A strong tendency to symmetrical development of the organ systems manifests itself in the syndrome of Polysplenia. These symmetrical organs show the anatomy of leftsided structures. For this reason the syndrome is also referred to as the "syndrome of bilateral leftsidedness". It encompasses complex abnormalities of situs, typical cardiac and vascular deformities as well as extracardiac malformations. Polysplenia is the leading symptom. Diagnosis is rarely made intra vitam. Certain typical deformities can give hints to this diagnosis, which is finally proved by szintigraphic and arteriographic visualization of multiple spleens. A typical case is reported and subsequently discussed according to the picture of this syndrome in the literature.

Abnormalities, Multiple↗

[Williams-beuren-syndrome (author's transl)].

In the initial descriptions of the elfin-facies-syndrome by Williams and Beuren, supravalvular aortic stenosis was considered to be a constant feature of the syndrome, combined with retardation of mental and physical development, dentition anomalies and the peculiar face. According to newer findings, the missing of this deformity is no proof against the existence of the above-mentioned syndrome. Usually an elevation of the calcium-level is not found in the serum of these children, although there seems to be some relation to the calcium-metabolism. The characteristic picture of this deformity is demonstrated by two, very typical cases.

Abnormalities, Multiple↗