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Biomedical subjects

A Benigno

Publications and source records attributed to A Benigno.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Time course analysis of the effects of intrapeduncular injection of kainic acid on amygdaloid paroxysmal activity].

Intrapeduncolar intrapeduncolar entopeduncolar injection of kainic acid determines an early decrease of the evoked amygdaloid paroxysmal activity, and a later increase of the AD length. The diphasic effect of the injection of kainic acid into the entopeduncular nucleus is likely due to the structural analogy of this drug with a neuroexcitant amino acid, monosodium glutamate. The inhibitory role of the entopeduncolar nucleus on the paroxysmal phenomena evoked in the amygdala is emphasized.

Animals↗
PubMed1981

Adaptative processes in the albino rat raised under hypoxia at simulated altitude.

Albino rats of the Wistar family were raised from the time of birth in a simulated altitude of about 6000 meters (barometric pressure 370 mm Hg) for a period of about 50 days. Part of these were killed after losing consciousness upon exposure to acute hypoxia. The other groups were killed without being first subjected to acute hypoxia. Control groups of the some stock were raised for a corresponding period of time in a normal atmosphere at sea level and killed like the preceding. We were not able to demonstrate significant variations in tolerance to acute hypoxia in the various groups studied. Instead the animals raised in a simulated altitude displayed an increase in the 2,3-DPG content in the red blood cells, Hb concentration and the number of erythrocytes for mm3 of blood. The animals raised in a simulated altitude also displayed a displacement of the acid-base balance of blood towards the acid side. This was even more accentuated in the group subjected to acute hypoxia. Finally, it was observed, via the weight curve, that the animals raised in a simulated altitude presented a slower body growth in comparison to the control group.

Acid-Base Equilibrium↗
PubMed1980

Observation on the reactions of the albino rat in simulated altitude.

Albino rats of the Wistar family were reared from the time of birth in a simulated altitude of about 6000 meters (barometric pressure 370 mm Hg) for a period of about 50 days. A number of these were killed after losing consciousness upon exposure to acute hypoxia. The others were killed without being first subjected to the acute hypoxia. Control groups of the same stock were reared for a corresponding period of time in a normal atmosphere at sea level and killed like the previous group. The animals reared in a simulated altitude displayed an increase in the 2,3-DPG content in the red blood cells, Hb concentration and the number of erythrocytes for one ml of blood. They are to be considered phenomena of adaptation, only slightly influenced by the acute hypoxia. The animals reared in a simulated altitude also displayed a displacement of the acid-base balance of the blood towards the acid side. This was even more accentuated in the group subjected to the acute hypoxia. It was observed, via the weight curve, that the animals reared in a simulated altitude presented a slower body growth in comparison to the control group. We were not able to demonstrate significant variations in the tolerance to acute hypoxia in the various groups studied.

Acid-Base Imbalance↗
PubMed1976

[A study of arterial pressure, pulse rate and capnogram during exhaustive muscular work performed by healthy subjects while breathing air or 100% oxygen (author's transl)].

Eight untrained healthy young men were submitted to exhaustive physical exercise, performed on a bicycle ergometer while breathing either air or 100% oxygen, Arterial pressures, pulse rate and, in some instances, capnogram too were recorded during exercise and at the end of it. In the majority of subjects, 100% oxygen breathing was found to improve in some way work performance, in comparison with air breathing. However, the differences in the parameters examined appeared to be subjective and inconstant and to change according to work load levels.

Adult↗