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A Berre

Publications and source records attributed to A Berre.

11 recordsLinked to original sources

[Inefficacy of theophylline in preventing hypoxemia in abdominal surgery].

It would be very useful to prevent post surgery ventilatory and gazometric insufficiencies that represent a significant risk factor. Ten patients have received proper doses of theophyllin in order to maintain accurate plasmatic concentration immediately after surgery. During the next 24 hours, their respiratory frequency, tidal volume, ventilation per minute, PaO2 and PaCO2 have been recorded. Those data have been compared with a test group (N = 10) having received injections of placebo. No relevant discrepancy exists in the ventilation parameters nor any increase of PaO2. The significant factor is a substantial decrease of PaCO2. It appears that theophyllin has no significatory efficiency for controlling the post surgery hypoventilation and hypoxemia.

Abdomen↗

[Adsorption of insulin directly added to infusion bottles].

A study of insulin adsorption to infusion system was undertaken in the situation of direct addition of insulin alone in the infusion bottles, with use of 125I-labelled insulin and non labelled insulin. The infusion solutions tested were glucose solutions (5, 10, 15 and 30%). There is an important adsorption of insulin (75%) to the infusion system when the insulin concentration in the solution is low. The effluent insulin is not degraded. The glucose content of the solution does not influence the phenomenon. Adsorption of insulin decreases when the insulin concentration in the solution is increased and a plateau is reached starting from an insulin concentration in the solution of about 400 ng/ml; at higher concentrations, 80 to 90% of insulin that has been initially put in the bottle is recovered. Since the insulin concentrations in the solutions used in clinical practice are higher than 400 ng/ml, this adsorption phenomenon can be neglected and therefore can explain the efficiency of this mode of insulin-therapy. Kinetics of effluent insulin is a plateau, stable all along the infusion. Thus, direct addition of insulin alone into infusion bottles is an efficient and controlled mode of insulin-therapy if a minimal insulin concentration in the infused solution has been reached.

Adsorption↗

[Adsorption of insulin introduced directly into perfusion bottles].

A study of insulin adsorption to infusion system was undertaken in the situation of direct addition of insulin alone in the infusion bottles, with use of 125I-labelled insulin and non labelled insulin. The infusion solutions tested were glucose solutions (5, 10, 15 and 30%). There is an important adsorption of insulin (75%) to the infusion system when the insulin concentration in the solution is low. The effluent insulin is not degraded. The glucose content of the solution does not influence the phenomenon. Adsorption of insulin decreases when the insulin concentration in the solution is increased and a plateau is reached starting from an insulin concentration in the solution of about 400 ng/ml; at higher concentrations, 80 to 90% of insulin that has been initially put in the bottle is recovered. Since the insulin concentrations in the solutions used in clinical practice are higher than 400 ng/ml, this adsorption phenomenon can be neglected and therefore can explain the efficiency of this mode of insulin-therapy. Kinetics of effluent insulin is a plateau, stable all along the infusion. Thus, direct addition of insulin alone into infusion bottles is an efficient and controlled mode of insulin-therapy if a minimal insulin concentration in the infused solution has been reached.

Adsorption↗

[Technic of continuous axillary plexus block].

A technique of continuous axillary brachial plexus block, using an epidural Tuohy needle and an epidural catheter, is described. Studies were carried out in ten patients using this technique with bupivacaine as a local anesthetic drug. The catheter remained indwelling during a mean period of five days. Good analgesia was obtained in nine out of the ten patients. Thus this technique allows pain-free postoperative period in hand surgery.

Axilla↗

[Discriminant factors of risk of infection in routine digestive surgery. Trial apropos of 308 cases].

Postoperative infection in routine digestive surgery is a common complication, its prevalence being variously assessed between 10 and 30%. Study of criteria of infectious risk, whether inherent to the subject or his environment, has not been the subject of overall evaluation. The present study involved 308 subjects in two departments of surgery with different geographical and architectural features. A comparison was first made between the two departments in terms of the surgical population and the reaction rate. The presence was then sought of a relationship between infection, whether general or local (urinary tract, pulmonary, septicaemia) and factors concerning the bacteriological environment and factors indicative of the resistance of the subject. The statistical technique of discriminant analysis was used to determine the preponderance of certain factors which might be indicative of at risk subjects.

Adult↗