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Biomedical subjects

A Bilgiç

Publications and source records attributed to A Bilgiç.

61 records · Page 4Linked to original sources

Congenital double-orifice mitral valve. A case report.

A three-year-old girl was admitted to Hacettepe Children's Hospital due to sweating and poor feeding. Echocardiography demonstrated ostium primum atrial septal defect with a cleft mitral valve. After two months of medical follow-up with digitalis, she was subjected to open-heart surgery, and a primum-type atrial septal defect with double mitral orifice was found. To avoid creating acute mitral stenosis, the cleft was only partially sutured and the septal defect was closed with a patch. Her postoperative recovery was uneventful. It is emphasized that surgical intervention should be individualized in each case.

Child, Preschool↗

Congenital absence of the pulmonary valve associated with pulmonary stenosis, large ductus arteriosus and intact ventricular septum. Case report.

A six-day-old neonate was diagnosed with a severe form of the syndrome of absent pulmonary valve associated with pulmonary stenosis, aneurysmal dilatation of the pulmonary artery and rare findings including an intact ventricular septum and large ductus arteriosus. The patient underwent surgical repair by closed technique. Cardiac catheterization data, hemodynamic and clinical findings, and surgical technique are reported. Congenital absence of the pulmonary valve is a rare cardiac anomaly. An especially severe form occurs with ventricular septal defect and pulmonary stenosis. The usual findings are respiratory distress, aneurysmal dilatation of the pulmonary arteries and pulmonary stenosis.

Ductus Arteriosus, Patent↗

"Acquired" subvalvular aortic stenosis after repair of several congenital cardiac defects.

Discrete subvalvular aortic stenosis is a progressive lesion. In this report we presented nine patients who had no significant left ventricular-aortic obstruction at initial cardiac catheterization or echocardiographic examination, but later developed significant subvalvular aortic stenosis. Associated lesions included ventricular septal defect in three, patent ductus arteriosus in two, aorticopulmonary window in one, tetralogy of Fallot in one, supramitral membrane in one, and ventricular septal defect and patent ductus arteriosus in one case. Nine patients were diagnosed with subvalvular aortic stenosis 18 months to eight years after surgical correction. Eight of the patients required surgery for subvalvular obstruction. In conclusion, discrete subaortic stenosis is a rare, late complication of the surgical repair of several congenital heart defects. It is a progressive lesion after surgery; therefore these patients require careful follow-up.

Aortic Stenosis, Subvalvular↗

Blade atrial septostomy: experience with 18 patients.

Blade atrial septostomy was performed in 18 patients, including 14 with transposition of the great arteries, three with tricuspid atresia and one with severe mitral stenosis and ventricular septal defect. The patients' ages ranged from 25 to 210 days (mean: 108 +/- 64 days), and weights ranged from 3.0 to 6.0 kg. Following blade septostomy, partial arterial pressure of oxygen (PaO2) increased from an average of 22 +/- 3.3 mmHg to 38.9 +/- 7.6 mmHg (p < 0.001), and prompt clinical improvement was observed in the majority of patients. Significantly decreased atrial pressures (from 8.16 +/- 6.1 to 3.93 +/- 2.2 mmHg, p < 0.01) and significantly enlarged inter-atrial openings (from 1.6 +/- 0.9 to 7.5 +/- 1.8 mm, p < 0.001) were achieved with successful blade atrial septostomy. Blade atrial septostomy is an effective and life-saving procedure in patients who require nonrestrictive inter-atrial communication.

Echocardiography↗

Intradermal administration of hepatitis B vaccine in infants and preschool children.

One of the ways to administrate hepatitis B vaccination is the intradermal (id) route. The aim of this study is to evaluate the immunologic response of various age groups of children who received three 2 micrograms id doses of recombinant hepatitis B vaccine. One hundred and eighty-seven children (86 infants, 101 preschool children) were administered a 2 micrograms dose of recombinant hepatitis B vaccine (Gen Hevac B) intradermally zero, one and six months. Eight weeks after the third vaccination, the geometric mean titers (GMT) of antibody to hepatitis B surface antigen (anti-HBs) of infants was 753 IU/L; that of preschool children was 799 IU/L. There was no statistically significant difference between the anti-HBs GMT of infants and preschool children. However, infants were less likely to have developed protective anti-HBs (< or = 10 IU/L) than preschool children (93% vs 100%, p = 0.009). In 8.1 percent of infants and 3.9 percent of preschool children, local reactions were observed. The 2 micrograms recombinant vaccine by id route is safe and suitable for immunization of preschool children. The id route is technically difficult to administrate in infants and protective seroconversion rates are lower than in preschool children.

Child, Preschool↗

Interruption of the distal left pulmonary artery with pulmonary arteriovenous fistulas and atrial septal defect.

A seven-year-old boy with interrupted left pulmonary artery, arteriovenous fistulas and atrial septal defect is presented. The anomalies were identified by echocardiography and angiography. On pulmonary artery angiograms, left pulmonary artery discontinuity (as though the distal segment had been interrupted), diffuse granulary opacification of right lung fields, and early visibility of the left atrium were observed.

Arteriovenous Fistula↗