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Biomedical subjects

A Bolanca

Publications and source records attributed to A Bolanca.

7 recordsLinked to original sources

Tumor marker determinations.

A combination of 2 or 3 tumor markers was determined in the serum of 478 patients with malignant tumors. In 195 out of 213 patients with differentiated thyroid cancer and without relapse or metastases, the Tg concentration has undetectable. In 9 patients with nonfunctioning thyroid metastases the Tg level was correlated with the progress of the disease or the success of the treatment. In 114 patients with gastrointestinal cancer CA 19-9, TPA and IAP were measured simultaneously. The highest discrepancies between patients with relapse or metastases (increased values in 1/2 of patients) and patients without relapse or metastases (increased values in 1/4 of patients) were given by CA 19-9. In the serum of 90 patients with breast cancer increased CA 15-3 values were found in 2/3 of patients with relapse or metastases and in 1/4 of patients without signs of tumor. A combination of universal tumor markers TPA and IAP had no value in monitoring 26 patients with melanoma.

Biomarkers, Tumor

[Is an early diagnosis of neoplastic processes of the rectum possible?].

The better operative results and lasting cure of malignant tumors can be ascribed to early detection rather than to the improvement of surgical techniques. In the cancer of the breast and gynecological carcinoma the importance of early detection has been more emphasized than in cancers of other location. On a total of 5210 rectoscopies performed the authors detected 285 malignant tumors of the rectum. On the average the diagnosis was made 9 months after the appearance of the first symptoms. In 74% of cases the tumors were detected already by the digital examination, while in 46.9% of the rest of the patients inoperable carcinoma was involved. By obligatory digital examination in all cases of "hemorrhoidal" complaints and additional rectoscopy neoplasms of the rectum can be detected at an early time and more patients can be afforded lasting cure.

Adolescent