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Biomedical subjects

A Bollar

Publications and source records attributed to A Bollar.

15 recordsLinked to original sources

[Schistosomiasis of the spinal cord. Case report].

The authors report a case of a 34 year-old woman who, in the last four years, had travelled to Africa frequently, and developed a progressive clinical (about three months) dysfunction of the conus medullaris mainly consisting in sensitive disturbances. The MRI showed an intramedullary spinal cord lesion, and specific laboratory tests were negative. A biopsy for histologic diagnosis, showed a granulomatous tissue with eggs of S. Hematobium. After this diagnosis she was treated with praziquantel. We emphasize the relative frequency of the spinal cord location of schistosomiasis in endemic countries, and the importance of the laboratory diagnosis to start an early and effective antischistosomal treatment. Spinal cord schistosomiasis is uncommon but we must bear in mind this possibility in patients with a progressive spinal cord afectation.

Adult↗

[Cervical intramedullary neurofibroma].

Spinal neurofibromas make up a third of all tumours of the medulla. They are usually found to be intradural and extramedullary. Exceptionally they may be intramedullar. We describe the case of a patient with signs of slowly progressive compression of the medulla, who was operated on surgically for an intramedullary neurofibroma, after imaging studies. We review the previously published cases and analyse the different histogenic theories concerning this tumour.

Female↗

Indicators of hypoxia in cerebrospinal fluid of hydrocephalic children with suspected shunt malfunction.

We used high performance liquid chromatography to determine the concentration of purine metabolites in the cerebrospinal fluid of three hydrocephalic children with a history of shunt malfunction. Hypoxanthine and xanthine levels were high in comparison with controls. We consider these purines to be valuable indicators of disturbance of neuronal metabolism following the sustained rise in intracranial pressure caused by shunt valve malfunction.

Adolescent↗

Sinus pericranii: radiological and etiopathological considerations. Case report.

Sinus pericranii is a rare vascular anomaly involving an abnormal communication between the extracranial and intracranial circulations. A case of frontal sinus pericranii is presented which appeared to be a posttraumatic sinus because it developed 2 years after a cranial injury. However, the presence of vascular endothelium in the pathological examination and its association with a vascular anomaly (persistent trigeminal artery) suggested a congenital origin. The lesion, pericranial blood sinuses, and bone were totally removed. The computerized tomography, angiography, and magnetic resonance imaging findings are presented. The literature is reviewed and the pathogenesis of sinus pericranii is discussed.

Adult↗

Hydrocephalus and intraspinal tumor in childhood.

Hydrocephalus with spinal tumor is rare, and its cause is obscure. We report one patient with a thoracic astrocytoma who developed ventricular dilatation and intracranial hypertension. The pathophysiology is reviewed.

Astrocytoma↗

Brain cysticercosis treated with praziquantel. Report of six cases.

Cysticercosis is the most common parasitosis affecting the central nervous system and it is endemic in many countries. Although cysticercosis is nowadays a rare disease in Spain, three of such cases have been treated with Praziquantel at the Hospital "Princesa Sofía" of León and another three at the Hospital General de Galicia of Santiago, and the six of them are reported together. The six patients presented at CT scans cysts located at different levels in the brain parenchyma, subarachnoid space and ventricular system. Praziquantel was administrated at daily dosage of 50 mg per kilogram of body weight, by oral route, distributed in three doses during 15 days. Moderate hepatotoxic effect were detected in two cases. No significant neurological disfunction was observed in any case during the treatment. The therapeutic effect on the brain cysts was evaluated in the CT scans obtained after treatment. In four cases a positive effect on the cysts was observed, but no apparent effect was noticed in the other two.

Adult↗