[Technic and results of interstitial radiotherapy of the pititary in various endocrine syndromes: chromophobe adenoma, acromegaly and Cushing's disease].
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Biomedical subjects
Publications and source records attributed to A Bonis.
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The authors present the tele-E.E.G. resording of three episodes of PM status, occurring in three known epileptics (ages: 16, 20 and 22 years). One episode was induced by an injection of bemegride and the other two by overbreathing. Their duration was 27, 31 and 44 minutes respectively. The development of abnormalities was progressive in all three cases, whilst they disappeared suddenly in two cases. Study of these three episodes was made in two ways: an electrical study and a clinical study. In addition, a brief retrospective study of the psychological experience of the episodes was carried out. The main finding was that the three episodes recorded and observed represented prolonged attacks and not a succession of attacks. The authors concluded that episodes classified under the name of PM Status may be studied in two ways: either considering them as prolonged attacks which are not status epilepticus, or considering them as repeated attacks, their repetition resulting in the appearance of unusual additional signs and which are status epilepticus.
The authors study the role of amygdala dysfunction in cases of oro-alimentary signs occuring in seizures recorded during a series of stereo-electroencephalographic investigations (S.E.E.G.) carried out for neurosurgical purposes. The patients under study have an epilepsy that is resistant to drug therapy. This work concerns 89 seizures with "oro-alimentary motor activity" recorded in 59 patients with whom it was possible to establish sufficiently rigourous anatomical - electrical - clinical correlations. This study enabled us to show that : --a seizure characterized by "oro-alimentary motor" signs (with the exclusion of swallowing movements) is related to a discharge that directly involves the amygdala. --a critical discharge affecting the anterior temporal region is expressed as : oro-alimentary activity either accompanied or not by other signs (breaking contact is exceptional). --late "oro-alimentary motor activity" also indicates disorganization of the amygdala, but offers no conclusion on the origin of the discharge.
The literature only rarely mention the genital and sexual manifestations occurring in the course of partial seizures in man. The authors presently describe 42 seizures of this type recorded with E.E.G. and Stereo-E.E.G. techniques in 15 patients. The results of this study indicate that the genital and sexual paroxystic manifestations do have a specific semeiology, and there can be related to the initial localization of the electrical discharge which may begin in one of three different regions (perisylvian region, anterior part of the cingular gyrus and the paracentral lobule). Penile erection is observed in only one seizure starting in the central region. Orgasm occurs in the only one female patient in the course of the seizures beginning in the perisylvian region (temporal region). Early sensitive symptomatology characterizes very often the seizures beginning in the perisylvian region but also in the paracentral lobule. Post-ictal or peri-ictal true masturbation occurs at the end of the ictal discharge beginning either in the perisylvian region or in the anterior part of the cingular gyrus. The sexual dyspraxic (i.e. fondling the genitals) characterizes only the post-ictal phase of the seizures beginning in any of the three regions.
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