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Biomedical subjects

A Bourgeade

Publications and source records attributed to A Bourgeade.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Imported falciparum malaria in Marseilles hospitals in 1987. Apropos of 104 cases].

Patients were composed of 85 adults and 19 children; 70 were European, 23 Comorian; malaria was contracted by 9 patients in French Guyana, 60 in Africa, 23 in Comoro Islands; prophylaxis was correct for 45 patients (nearly all of the cases with chloroquine) when the first symptoms occurred. Every case of malaria appeared during the month following their return from an endemic area. Fever was often moderate or intermittent, altered by prophylaxis and previous treatments. Some patients had a clinical profile of "visceral evolutive malaria" and 3 a cerebral malaria. The most frequent biologic alteration was thrombopenia (40 times under 100,000/microliters). No relation between parasites density and clinical profile has been identified. The sensitivity of the strains for antimalarial drugs has been studied 35 times: 28 strains were chloroquine resistant, 3 have a decreased sensitivity for quinine. Most of the resistant strains came from Central Africa. Two patients died.

Adolescent↗
PubMed1989

[Current clinical aspects and role of parasitic density in the manifestations of falciparum malaria].

56 patients carriers of Plasmodium falciparum were observed throughout 1987: 47 males and 9 females of a mean age of 32. The following clinical aspects were observed: Falciparum malaria: 35 cases, malaria with a low parasitaemia (less than 1,000 HPM): 5 cases, tropical splenomegaly syndrome: 3 cases, isolated bi- or tricytopenia: 10 cases, cerebral malaria: 1 case, asymptomatic carriers: 2 cases. Statistically speaking, no significant correlation was observed between parasitaemia and the following clinical and biological symptoms: fever, splenomegaly, Hb level, platelet count. However, we noted a level of parasitaemia higher in the acute forms of malaria (Falciparum malaria and cerebral malaria) than in the non typical forms (chronic visceral malaria, haematological disorders). All asymptomatic carriers, who represent "malaria infection", presented a low parasitaemia (less than 1,000 HPM).

Adolescent↗
PubMed1989

[Resistant falciparum malaria at the F. Houphouet-Boigny hospital in Marseilles in 1985-1986-1987].

Chemoresistant P. falciparum malaria emerged in South Sahara Africa during 1978 and is now more than half of the imported malaria in F. Houphouet-Boigny Hospital in Marseilles (France), consequently the annual number of malaria cases has doubled as compared to the previous years. In our study of 47 chemoresistant malaria cases, collected in 1985-1986-1987, mostly contracted in French-speaking Africa, residents and travellers were both equally affected. Curative treatment was quinine IV for severe malaria (34%), sulfadoxine-pyrimethamine (46.8%), and mefloquine (51%).

Adult↗
PubMed1989

[32 cases of recurrent localized edema on return from the Tropics].

Thirty-two patients have been hospitalised in Marseilles since 1979 for recurrent oedema following their return from a tropical region. In spite of strong suspicion, the diagnosis of Loa loa was confirmed only five times. One patient was diagnosed with filariasis due to Mansonella perstans. The diagnosis of loiasis was usually presumptive and there were often wide variations in the laboratory findings. Two patients were thought to have an allergic reaction to diethylcarbamazine. Another patient was felt to have an allergy to streptococcal antigen. One patient who had lived in the Extreme Orient presented with an inflammatory fasciitis. Two patients presented with neurological manifestations: one with eosinophilic meningo-encephalitis, one with a neuropathy of the median nerve. In one case, the oedema was attributed to congenital lymphoedema.

Adolescent↗
PubMed1985

[African trypanosomiasis of icterohemorrhagic form].

A case report of trypanosomiasis (T. rhodesiense), observed in a French tourist is described. The clinical picture associated a cytolytic hepatic jaundice, a thrombopenia with hemorrhagic manifestations, a renal insufficiency and secondarily a neutropenia with anemia. Moderate and transitory anomalies in the cerebrospinal fluid were noted. The cure was effectuated by administration of pentamidine.

Eflornithine↗
PubMed1985

[Trichinosis in Provence. Apropos of a familial epidemic].

An outbreak of trichinosis following meals in a rural area of Provence is reported. The epidemiologic parameters reconstitute the contamination cycle (man-pig: fox-rat) which indicated indisputably the diagnosis, the appropriate therapy, and also evidenced a rural zoonosis of trichinosis in Provence. The clinical picture among twenty-one people included morbilliform rash in 38% of cases and an enanthema in 24% of cases, uncommon findings, with respect to their frequency, and the other usual signs. Early laboratory diagnosis was made possible by blood analysis for hypereosinophilia and immunoassay (ELISA) for antigen-specific IgE. Treatment with benzimidazoles was quite effective.

Adult↗