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Biomedical subjects

A Bourlond

Publications and source records attributed to A Bourlond.

10 recordsLinked to original sources

[Epidermotropic reticulosis of the Woringer-Kolopp type (author's transl)].

A 46-year-old female, otherwise healthy, developed erythematous, pseudotumoral nodules, mainly on the hands; biopsies led to the diagnosis of Woringer-Kolopp disease. Anti-anergic chemotherapy with levamisole proved hazardous but, possibly, beneficial. Classification into benign localized, fatal generalized and intermediate disease is briefly commented upon. Differential diagnosis and tumor origin are discussed; while the Merkel cell hypothesis has been recently advanced strong analogies and slight discrepancies with mycosis fungoides advocate the T cell lymphoma theory.

Diagnosis, Differential

Cutaneous innervation.

This is a review of historical facets of research in cutaneous neurohistology. The silver stains, used for some 150 years, led to the discovery of the neurone theory and to contemporary comparative studies. The cholinesterase methods, used since 1950, are the most convenient for general studies of nerves. The fluorescence technique of Falck (1962) is valuable for the study of adrenergic fibers. The electron microscope techniques used since 1950 have allowed the comprehensive description of myelinated and unmyelinated nerve fibers and of corpuscles. The most important unsettled questions pertain to the physiology of cutaneous nerves and precise definitions of cutaneous sensibility.

Animals

[Eczema herpeticum. Clinical observation and ultrastructural study].

A child afflicted with atopic dermatitis developed a Kaposi-Juliusberg's syndrome. Virological and ultrastructural investigations proved a widespread herpes virus infection. Maturation of the virus within the nuclei of epidermal cells and its release into the cytoplasm and the intercellular space have been studied at the ultrastructural level and some peculiar data brought up.

Dermatitis Herpetiformis