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A Bozzao

Publications and source records attributed to A Bozzao.

45 records · Page 3Linked to original sources

Wernicke encephalopathy: MR findings in five patients.

Wernicke encephalopathy is a disease usually related to chronic alcoholism. The clinical diagnosis is often difficult to establish, and CT is unable to provide specific findings. MR follow-up studies in five patients affected by Wernicke encephalopathy were performed with the aim of establishing the sensitivity of MR in depicting the typical diencephalic/mesencephalic lesions. All subjects had MR imaging in the acute phase of the disease and were reexamined 6-12 months later, at which time they were in good health. Three of them also had CT scanning. On MR, hyperintense areas seen surrounding the third ventricle and aqueduct during the acute phase of the disease had disappeared or diminished on follow-up evaluations. The third ventricle and aqueduct were dilated. We suggest that these findings reflect the natural evolution of Wernicke encephalopathy. The MR findings in Wernicke encephalopathy enable early diagnosis of the disease, which has a positive effect on both treatment and prognosis.

Acute Disease↗

The usefulness of dynamic CT in patients with aneurysm of Willis circle. Comparative study with the angiography.

The diagnosis of cerebral aneurysm is currently based on the angiographic data. We have tried to evaluate the usefulness of a less-invasive examination, such as the dynamic-CT, in the diagnosis of intracranial aneurysm and of the possible and concomitant subaracnoid haemorrhage. The CT examination is useful in the diagnosis of both subarachnoid haemorrhage and giant trombosed aneurysm. It is less reliable than the angiography as regard to aneurysm of small dimension.

Adult↗

Neoplasms of the optic-chiasmatic region.

Diagnosis of neoplasms of the optic-chiasmatic region is facilitated by assessment of onset symptoms. They represent the basis for a specific radiologic study, allowing a differential diagnosis between radiologically similar forms. An easy approach to these neoplasms is to separate malignant lesions from non-neoplastic space-occupying lesions. Diagnostic imaging of neoplasms of the optic-chiasmatic region is based on MRI, occasionally combined with CT. Because of its peculiar embryology, the region is the site of numerous neoformations. However, differential diagnosis is ready in most cases. To plan the most suitable surgical management, the relations of the lesions with adjacent anatomical structures should be carefully assessed. More complex syndromes (gliomas in NF1, infundibulopeduncular histiocytosis in eosinophilic granulomatosis, etc.) should also be considered.

Child↗

Enhanced and unenhanced MR with magnetization transfer in multiple sclerosis.

PURPOSE: To evaluate the use of magnetization transfer and the apparent enhancement of lesions on contrast-enhanced MR images in patients with multiple sclerosis. METHODS: Contrast-enhanced T1-weighted spin-echo MR images obtained in 20 patients with relapsing-remitting multiple sclerosis, with and without magnetization transfer, were evaluated to determine the number of enhancing plaques. Comparison was made with unenhanced T1-weighted magnetization transfer images. Contrast-to-noise ratios were obtained for these lesions on both the enhanced and unenhanced magnetization transfer T1-weighted spin-echo MR images. RESULTS: Ten plaques were considered enhancing only when the enhanced magnetization transfer T1-weighted images (11% or more) were used; however, they were all hyperintense on unenhanced T1-weighted magnetization transfer images. The contrast-to-noise ratios of these lesions were 16.52 for the enhanced images and 15.65 for the unenhanced images. The two values were not statistically different. CONCLUSIONS: In patients with multiple sclerosis, examination with contrast-enhanced magnetization transfer MR images alone may overestimate the number of enhancing plaques.

Brain↗