Biomedical subjects

A Brázda

Publications and source records attributed to A Brázda.

7 recordsLinked to original sources

PubMed2002

[An unusual tumor of the oral cavity in a fetus and prenatal ultrasonography--case report].

OBJECTIVE: The tumours and pseudotumours of the foetal face are very rare diseases. Basic method for their prenatal diagnosis is ultrasound. The authors describe the case of diagnosed orofacial pseudotumour--sublingual cyst. DESIGN: Case report introduces some rules for ultrasound investigation of foetal face. SETTING: Department of Clinical Genetics and Foetal Medicine, University Hospital Olomouc. SUBJECT AND METHOD: The cyst of oral cavity was diagnosed by ultrasound in second trimester of gestation. It was repeatedly punctured during pregnancy and the content was cytologically examined. Exstirpation was performed after delivery. Histological etiology--dysontogenetic cyst--was established. CONCLUSION: Prenatal ultrasonographical diagnosis of the oral pseudotumour was completed by puncture procedures. This invasive way verifies anatomical conditions, enables histological investigation and warrants the swallowing act which is the prevention of polyhydramnion.

Adult↗

PubMed1993

[The basal cell nevus syndrome. Case report of a 14-year-old girl].

"Basal cell naevus syndrome" (Gorlin's syndrome) is a sporadic autosomal dominant hereditary precancerous condition which affects several organ systems. The dominating clinical manifestations are multiple basal cell naevi which develop into malignant basocellular carcinoma. Further abnormalities include abnormalities of the vertebrae and ribs, odontogenic keratocysts, calcification of the falx cerebri, a special facial appearance with progeny and macrocephaly. Affected patients may develop also ovarian fibromas, fibrosarcomas, cardiac fibromas, medulloblastomas and meningiomas. Lymphatic and chylous mesenteric cysts are also frequent. In the submitted paper the authors present the case-history of a 14-year-old girl with multiple naevi, histologically specified as solid, superficial and tricho-epithelial basalioma. Phenotypic manifestations, multiple keratocysts, bone abnormalities and calcifications of the falx cerebri which are detected in the girl led to the diagnosis of Gorlin's syndrome. The authors discuss the problem of cytogenetic findings (structural abnormalities, markers of mutagenicity) and possible therapy.

Adolescent↗

PubMed1988