A Brady — Page 2 | PubMed Health

PubMed1987

Vascular access options for outpatient cancer therapy.

Knowledge of the abilities and limitations of various access devices can help the surgeon decide which is best matched to an individual cancer patient receiving outpatient therapy. Implanted ports have become the mainstay of long-term treatment. Hickman catheters are useful for long-term nutritional support and pain control when parenteral narcotics are required. Long-arm catheters and central venous catheters can be utilized for short-term therapy. Proper utilization of the various vascular access devices can optimize patient care in a cost-effective manner.

Ambulatory Care↗

PubMed1987

Relative novelty of conditioning context influences directionality of glycemic conditioning.

Previous experiments in which insulin was administered in a Pavlovian conditioning procedure obtained both hyperglycemic and hypoglycemic conditioned responses (CRs). In the present experiment the relationship of the conditioning context and the housing environment was varied. Two environments, wastebasket (WB) and metal cage (MC), were varied factorially as housing and conditioning contexts. Subgroups were injected with either insulin or saline for 6 days and then, on a test day for conditioning, all animals were administered saline. The results suggested that a hyperglycemic CR could be expected when the conditioning context is different from the housing context, but a hypoglycemic CR could be expected when the conditioning context and housing context are similar. The magnitude and reliability of conditioning were greater when it was conducted in the WB context than when conditioning was conducted in the MC context. These results are discussed in terms of stress arising from relative novelty of the conditioning environment and in terms of the salience of the conditioned stimulus (CS) used in glycemic conditioning studies.

Animals↗