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Biomedical subjects

A Brunet

Publications and source records attributed to A Brunet.

At least 91 records · Page 5Linked to original sources

[Cervical spondylodiscitis. A rare complication of intubation].

The authors present two cases of cervical spondylodiscitis occurring following intubation. The most probably mechanism was direct contamination of the inter-vertebral disk through a lesion of the posterior pharyngeal wall, but other possible mechanisms for the spread of infection are discussed. This very rare complication should be borne in mind and routinely sought when there is persistence of cervical pain following intubation.

Aged↗

Metabolic enzymatic activities in the intercostal and serratus muscles and in the latissimus dorsi of middle-aged normal men and patients with moderate obstructive pulmonary disease.

The glycolytic and oxidative enzyme activities (lactate dehydrogenase (LDH), hexokinase (HK), citrate synthase (CS) and 3-hydroxyacyl-CoA-dehydrogenase (HAD] were measured in the fifth internal and external intercostal muscles, in the vertical and horizontal parts of the serratus, an accessory inspiratory muscle, and in a non-respiratory muscle, the latissimus dorsi (LD) of twenty middle-aged men: nine subjects with normal lung function and eleven patients with moderate chronic obstructive pulmonary disease (COPD). In the normal subjects the enzyme activities of the respiratory muscles were similar to those of the LD, and there were no differences between the internal and the external intercostal muscles. In the COPD patients the metabolic activities of HK, CS and HAD were higher in both intercostals than in LD. Furthermore, there was a significant increase in these enzymatic activities as compared to the intercostals of the normal subjects. These data support the hypothesis that the internal and external intercostal muscles play a more important role in COPD patients than in normal subjects. They are consistent with the hypothesis that COPD has an endurance training effect on both intercostal muscles which could compensate for diaphragmatic disuse.

3-Hydroxyacyl CoA Dehydrogenases↗

[Respective indications for free and pedicle flaps of the latissimus dorsi in maxillofacial surgery].

Retrospective analysis of 41 cases of transfer of free and pedicle musculocutaneous flaps of latissimus dorsi for selected or obligatory maxillofacial indications resulted in the review and critical assessment of the different modes of utilization of these flaps. Experience acquired, and continuously updated by new scientific data or a new clinical case, justifies the use of this exceptional technic, which should not be extended to include those cases able to be treated by simpler, more reliable methods. Similarly the fact that this muscle can be transferred using a microsurgical technic cannot enlarge its use beyond that motivated by reasoned medical imperatives. Modalities of preparation of the flap are described and its multiple applications demonstrated using several examples: indications for latissimus dorsi flap in maxillofacial surgery and reasons for performance of micro-anastomotic transfer.

Female↗

[Pulmonary arteriovenous aneurysm].

A case of large arteriovenous aneurysm in the right upper lobe of a 27-year old man is reported. The pulmonary angioma was responsible for a 30% shunt with hypoxia and polycythaemia but was only discovered while looking for the origin of a cerebral abscess. A few weeks after surgical treatment of the cerebral abscess, the right upper lobe was excised with immediate correction of the hypoxia. This case shows that pulmonary angiomas can sometimes be revealed by neurological complications, and that visceral angiomas should not remain undiagnosed. They should be considered as part of a Rendu-Osler disease, the familial character of which may contribute to an early diagnosis.

Adult↗

[Reno-caval thrombosis complicated by massive pulmonary embolism. Diagnostic and therapeutic problems].

The authors report on a case of thrombosis of vena cava and renal vein associated with a nephrotic syndrome and complicated by a massive pulmonary embolism. Under emergency conditions, it was impossible to diagnose preoperatively a renal tumor, which is the most common cause of renal and vena caval obstruction or a thrombosis of the vena cava. Surgical treatment was carried out only because there were no arteriographic signs of renal neoplasm, and because thrombolytic treatment was contra indicated in a patient with greatly reduced vital capacity. Embolectomy was performed under cardiopulmonary by pass. The patient made a good recovery. Results of routine cardiac and pulmonary tests were normal after two months. Embolectomy must always be associated with as interruption of the vena cava, whose different forms are discussed. Partial interruptions using a De Weese clamp seems to be better tolerated than ligation.

Diagnosis, Differential↗