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Biomedical subjects

A Budak

Publications and source records attributed to A Budak.

11 recordsLinked to original sources

[Monitoring of respiratory function in hemp-processing workers].

In a follow-up study the prevalence of chronic respiratory symptoms and changes in ventilatory capacity were followed over a period of three years in 38 female and 28 male hemp workers in a textile industry. The prevalence of all respiratory symptoms was found to be increased. Significant acute reductions of ventilatory capacity were recorded during the work shift. The measured ventilatory capacity values were significantly decreased in comparison to predicted normal values. The mean annual decline of FVC (range: 0.014-0.065 L), FEV1 (range: 0.041-0.068 L), FEF50 (range: 0.020-0.220 L/s) and FEF25 (range: 0.030-0.140 L/s) was considerably greater than in healthy non-exposed subjects. The mean annual decline of all tests was considerably larger in workers with the symptoms of byssinosis than in those without such symptoms. Our data suggest that long-term exposure to hemp dust may cause the development of chronic respiratory symptoms and impairment of ventilatory capacity.

Cannabis

[Immunologic reaction and ventilatory function in hemp-processing workers].

The relationship between immunological status and respiratory function was studied in 42 hemp workers and in 49 control workers. The highest prevalence of positive skin tests was recorded for a mixture of hemp and flax (64%), followed by flax (48%), hemp on a combining machine (41%), hemp on a carding machine (38%), hemp on spinning and weaving machines (33%), and hemp on a softening machine (20%). The prevalence of positive skin tests in control workers was smaller and varied from 21 to 5%. Increased IgE was found in 35.7% of the hemp workers and in 5.0% of the controls (P less than 0.05). Hemp workers with positive skin tests had a significantly higher prevalence of chronic respiratory symptoms than those with negative skin tests. Acute ventilatory capacity reductions did not differ in respect to the immunological status. An extract of hemp dust caused a constriction of an isolated guinea pig tracheal smooth muscle in vitro. Our data suggest that hemp dust as well as producing an immunological effect may exert an irritant effect on the respiratory system in exposed textile workers.

Adult

Epidemiology of Candida infection. I. Use of killer system for typing of Candida albicans strains.

A killer system was used for epidemiological differentiating of 350 Candida albicans strains isolated from human sources of different anatomical and geographical origin. By using 9 killer strains from genera: Hansenula, Pichia, Torulopsis, Saccharomyces it was possible to differentiate 87 killer types. Our findings showed differences in the occurrence of the types according to the origin of the strains. The killer system proves to be valid for the differentiation of strains within the Candida species for epidemiological purposes.

Bacterial Typing Techniques

Epidemiology of Candida infection. II. Application of biochemical methods for typing of Candida albicans strains.

Biochemical profiles of 350 C. albicans isolates from five towns in Poland and from Freiburg in Germany were determined on the basis of nine biochemical tests of Odds and Abbott method. API 20 C AUX system and additionally a resistogram. The analysis of the strains according to Odds' and Abbotts's system showed that investigated strains can be typed into 9 profile codes of common biochemical patterns. There were some differences among the profiles according to their geographical origin and anatomical sources of the isolation. On the basis of the ability C. albicans strains to assimilate of carbon sources, 350 isolates were categorised into 13 separate auxotrophic profiles with the major one: 2,576,174 accounting for 81% of the total. The majority of the investigated isolates were susceptible to antifungal agents (83%). A disproportionate distribution of auxotrophic profiles limited the use of resistogram method and API 20 C AUX as systems for typing C. albicans strains. On the other hand, the method of Odds and Abbott provides valuable criteria for typing of C. albicans.

Antifungal Agents

Epidemiology of Candida infection. III. A proposal for a new typing system for Candida albicans strains.

A proposal of a new typing system for C. albicans strains in this paper is presented. Our system was elaborated on the basis of computer analysis of the results received using various already existing methods (killer system, resistogram, API system and Odd's and Abbott's method) for typing of 350 C. albicans strains. The strains originated from various anatomical and geographical sources. For the new system we have chosen three characters: sensitivity to two killer strains (Pichia sp. STUMM 1035, Hansenula sp. STUMM 1034) and urea assimilation test. The computer-aided program, used as an analytical tool, permitted the selection of 8 types among the strains. The majority of tested isolates belonged to types 6 and 7. We observed differences in the distribution of types according to the geographical and anatomical origin of the strains. The criteria adopted in our system can be useful in typing of C. albicans for epidemiological studies.

Bacterial Typing Techniques

[Problems and recommendations for the care of refugees displaced by war in Croatia].

The present situation in Croatia and the principles of displaced person camp organization are described. Displaced person care has become the urgent problem imposed on the Croatian social service and health care system. The up to now work has revealed that their is a need for more precise categorization of displaced persons in order that a comprehensive registration system be developed. The number of registered displaced persons in Croatia up to 26 September 1991 is quoted. Based on problems noted in the organization of displaced person camps, elements of organization and known principles of health care system in Croatia, a new model of displaced person camp organization is proposed.

Humans