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Biomedical subjects

A Buffa

Publications and source records attributed to A Buffa.

4 recordsLinked to original sources
PubMed1991

Cell kinetics of vocal fold epithelium in rats.

In order to investigate the kinetics of vocal fold epithelium a bromodeoxyuridine-anti bromodeoxyuridine method has been applied in vivo at both light and electron microscopy level. This method is able to define the length of both epithelium turnover and cell-cycle in basal elements, as well as the existence of a higher proliferation rate during night time in comparison with day time. Moreover distinct labeling patterns observed in incorporating cells allow us to define the precise localization in S-phase of cycling elements.

Animals↗
PubMedDate not supplied

Examination of the factors Ac and Aeq for cylindrical ion chambers used in cobalt-60 beams.

The calibration of a cobalt-60 beam in a phantom with an ion chamber, which has been calibrated with respect to exposure, requires the use of a displacement correction factor which essentially corrects the photon fluence for the attenuation and scatter when the chamber with buildup cap is removed and replaced by phantom material. To determine the displacement factor, Ac, a special set of cylindrical ionization chambers with various volumes were constructed out of polystyrene. Tissue-air ratios were measured with these chambers for cobalt-60 gamma rays in a polystyrene phantom, and the ratio Ac/Aeq was experimentally determined. In order to calculate Ac from this ratio, Aeq was determined also. It was found that Ac depended on chamber diameter only, and not on field size or depth. A value of 0.990 for Aeq is recommended and a table of Ac for chambers of different outer diameters is included.

Cobalt Radioisotopes↗
PubMedDate not supplied

Electron backscatter corrections for parallel-plate chambers.

The wall of an ionization chamber is commonly assumed to have a negligible effect on chamber response in electron beams. For cylindrical chambers with thin walls this assumption is valid. However, parallel-plate chambers commonly possess large mechanical supports which may affect chamber response in a manner not accounted for in current dosimetry protocols. This is due to changes with energy in the relative backscattered electron fluence between chamber support and phantom materials. To investigate this effect, electron backscatter from low atomic number materials has been measured with electrons from 6 to 20 MeV. The effect of the diameter and thickness of the backscattering material has also been studied. Based on these data, Lucite and polystyrene chambers in water phantoms are expected to underrespond by 1% and 2% at 6 MeV. The expected underresponse decreases to 0.8% and 0.4% for polystyrene and Lucite at 12 MeV and is insignificant above 16 MeV. Two commercially available parallel-plate chambers were compared with a cylindrical chamber in electron beams from 6 to 20 MeV. Using the 20-MeV intercomparison, the expected chamber responses at the lower energies were calculated and compared with measurements. Both parallel-plate chambers underresponded by approximately 1% at 6 MeV and 0.5% at 9 MeV which is qualitatively consistent with the electron backscatter data. Recommendations for minimizing electron backscatter effects through chamber design are discussed.

Electrons↗