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Biomedical subjects

A Bugalho de Almeida

Publications and source records attributed to A Bugalho de Almeida.

5 recordsLinked to original sources
PubMed1991

Effect of drugs on histamine release.

The effects of histamine release in the pathogenesis of bronchial obstruction in asthma, and the action of several pharmacological agents on this release--both by prevention of this mediator's secretion and its antagonism, is briefly reviewed. It is concluded that some drugs can prevent either the histamine secretion or antagonize its effects, partially or totally, but some results must be carefully interpreted in what the clinical practice is concerned, as its practical application needs further investigation.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Ehlers-Danlos syndrome - a rare cause of spontaneous pneumothorax].

Ehlers-Danlos syndrome (cutis hyperelastica), is a group of connective tissue disorders characterized by abnormalities of the skin, ligaments and internal organs. It is a hereditary syndrome, usually with autossomal dominant inheritance; that primarily affects the collagen synthesis. The skin and blood vessels are extremely fragile and elastic. The skin is soft with rubber consistency and easily bruising. There are hypermobile joints with increased extensibility. We summarize the case of a sixteen year old boy with a history of joint hypermobility since childhood and splenic fracture that was diagnosed with Ehlers-Danlos syndrome after the occurrence of recidivant spontaneous pneumothorax. We present the most common pulmonary complications of Ehlers-Danlos syndrome and discuss the importance of not forgetting the least commons etiologies of pneumothorax, in cases of spontaneous pneumothorax.

Adolescent↗
PubMedDate not supplied

[Idiophatic mediastinal fibrosis: a case report].

We herein report a case of a male patient, who presented a mediastinal mass that had a slow growth over the years. After surgery, that made the diagnosis of idiopathic mediastinal fibrosis, the growth stabilized. Four years latter it was observed a substantial increase which lead to the inevitable compression of vital structures which, in turn, led to pulmonary hypertension. Idiopathic mediastinal fibrosis is an extremely rare pathology. There are same cases in which it is associated with other pathologies but has always a fatal prognosis when surgery is not an option.

Fibrosis↗
PubMedDate not supplied

[Transbronchial needle aspiration].

Transbronchial needle aspiration was initially invented in 1949 by Schieppati. After its adaptation to the flexible bronchoscope in 1983 by Wang this technique has gain firm indications in the diagnosis and staging of lung cancer, in peripheral pulmonary nodules and masses; in the evaluation of endobronchial masses; in the disease of submucosal, in benign diseases, i.e. sarcoidoses and mediastinal cysts and abscesses. The yield of this technique published in the literature makes it more than useful. The material available has different indications and usefulness in different clinical settings. Despite the almost absence of complications this procedure is yet underutilized, in spite of its twenty years of results which may be due to the established routines and the lack of training.

Biopsy, Needle↗