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Biomedical subjects

A Burt

Publications and source records attributed to A Burt.

45 records · Page 3Linked to original sources
PubMed1979

Diagnosis of primary thyroid carcinoma by immunohistological demonstration of thyroglobulin.

Thyroglobulin was found by the immunoperoxidase technique in routine histological sections of biopsies from all of 30 proven cases of well differentiated papillary or follicular thyroid carcinoma examined, in one of 20 anaplastic thyroid tumours and in none of 49 other tumours examined. Immunohistological demonstration of thyroglobulin in thyroidal or extrathyroidal tumours is of diagnostic value in confirming that the thyroid is the tissue of origin. Well differentiated tumours lacking thyroglobulin probably do not arise from thyroid epithelium.

Carcinoma↗
PubMedDate not supplied

Mammalian chiasma frequencies as a test of two theories of recombination.

A broad survey of asexuality in the animal kingdom is sufficient to reject all theories of sex and recombination except two: the Red Queen and the Tangled Bank. The Red Queen theory states that an organism's biotic environment tends to be 'contrary', consistently evolving to the detriment of the organism; sex and recombination result in progeny genetically distinct from their parents and grandparents and thus less susceptible to the antagonistic advances made during the previous generations, particularly by their parasites. The alternative theory, the Tangled Bank, states that sex and recombination function to diversify the progeny from each other, thus reducing competition between them. An extensive survey of mammalian recombination shows that the total number of chiasmata in excess of one per bivalent is strongly correlated with generation time but uncorrelated with fecundity. We conclude that crossing-over may function to combat antagonists with short generation times but does not function to reduce sib competition. Chromosome number is selectively neutral with respect to these factors.

Aging↗
PubMedDate not supplied

Vaccine site-associated sarcomas in cats: clinical experience and a laboratory review (1982-1993).

Recent information regarding vaccine site-associated sarcomas in cats suggest a relationship to either feline leukemia virus or rabies vaccines. The authors' initial case was in a cat that had received neither of these vaccines. Review of the available hospital records revealed an increasing number of vaccine site-associated sarcomas, none of which were related to feline leukemia virus vaccines. Only one was related to the use of a rabies vaccine, and this tumor occurred in the thigh as opposed to between the shoulder blades. The laboratory data supported an increasing incidence of vaccine site-associated sarcomas, the majority of which occurred in the interscapular area and were associated with routine prophylactic vaccinations.

Animals↗