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Biomedical subjects

A C Dixon

Publications and source records attributed to A C Dixon.

14 recordsLinked to original sources
PubMed2000

A journey toward womanhood: effects of an Afrocentric approach to pregnancy prevention among African-American adolescent females.

A Journey Toward Womanhood is an Afrocentric pregnancy prevention program for adolescent females developed by Sisterhood Agenda in Durham, North Carolina. In the present study, 33 past participants in the program were compared with 32 nonparticipants. Results suggested that the program had a positive impact, delaying the initiation of sexual intercourse, increasing contraceptive use among those who were having intercourse, and reducing the incidence of teen pregnancy.

Adolescent↗
PubMed1997

Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.

Sixty-one strains of bacteria capable of growth on 4-methyl benzoic acid (29 isolates) or naphthalene (32 isolates) as the sole source of carbon and energy were isolated from sediments and water samples from the River Tyne, UK. Random amplification of polymorphic DNA from genomic DNA extracted from the different strains demonstrated that 14 of the 4-methyl benzoate-degrading isolates were unique and the remainder fell into seven groups containing two or three isolates that produced identical banding patterns. Thirteen of the naphthalene-degrading isolates were unique and nine groups with two or three identical representatives encompassed all other isolates. Screening of the bacterial strains for the presence of genes homologous to xylE, nahC and bphC by polymerase chain reaction and dot blot hybridization demonstrated that most strains harboured xylE- and/or nahC-like genes and only a single isolate was found that did not harbour any of these genes. None of the isolates harboured bphC-like genes. It was concluded that, while considerable diversity existed in host strains isolated using a single simple enrichment procedure, the extradiol dioxygenase genes involved in aromatic ring cleavage, present in these strains, were conserved to a considerable degree.

Bacteria↗
PubMed1995

Self-perception changes among sports camp participants.

The relationship between sports camp participation and changes in self-perception was assessed. The participants were 42 boys and 32 girls participating in a 5-week summer sports camp for economically disadvantaged children in the United States. Self-concept was measured at the beginning and end of the camp with Harter's (1985) Self-Perception Profile (SPP) for Children. At the beginning of the camp the girls scored higher than the boys on overall SPP scores and three of six subscales. After 5 weeks, the girls' scores were higher on only one subscale and on adult group leaders' ratings. The decline in the girls' scores was attributed to the stress of competition or to initial overly positive self-perceptions.

Adolescent↗
PubMed1990

Outcome following open-heart surgery in an Oriental octagenarian population in Hawaii.

Increasingly, a surgical approach is being utilized for the management of elderly patients with ischemic or valvular heart disease. In order to further understand the outcome in this population, we performed a retrospective review of octagenarians undergoing open-heart surgery over a 2-year period. Thirteen patients were identified, with a mean age of 82.6 years. All were Oriental. Most of our patients were considered high risk, 10 of them requiring emergency surgery and 6 requiring preoperative intra-aortic balloon counterpulsation (IABP). Postoperatively, 11 of the 13 patients suffered at least 1 complication. The most frequent complications were atrial arrythmias (7 patients), a low cardiac output (5 patients), the need for prolonged ventilation (3 patients) and ventricular arrythmias (3 patients). Functionally, the patients statistically improved, from a mean preoperative classification of 3.8 (New York Heart Association Classification) (NYHA) to 1.5 at the time of discharge (p less than 0.001). All patients are still alive at the time of writing (October 1989) with a mean followup of 13.3 months. Our data show that an operative approach to heart disease can be done safely in a high risk octagenarian population. In addition, we found that a statistically significant functional improvement occurred in these patients.

Age Factors↗
PubMed1990

Plasmapheresis with exchange as primary treatment for thrombotic thrombocytopenic purpura.

Thrombotic thrombocytopenic purpura (TTP) is an uncommon disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever and renal and neurologic dysfunction. As a result of the availability of plasmapheresis, we can report the results of 5 patients treated with plasmapheresis and exchange transfusion who also received intravenous corticosteroids as adjunctive therapy. Our 5 patients had a mean age of 41 years, and presented with a mean platelet count of 39 x 10(9)/L. Four of the 5 patients responded to treatment and were discharged in excellent condition. The 5th patient succumbed to her disease. We concluded that plasmapheresis with exchange transfusion is a rapid and effective therapy for TTP.

Adult↗
PubMed1989

Strongyloidiasis associated with human T-cell lymphotropic virus type I infection in a nonendemic area.

Concomitant strongyloidiasis and human T-cell lymphotropic virus type I (HTLV-I) infection has been reported from areas in Japan where both organisms are endemic. We present four cases of concomitant infection with these organisms from an area that is not endemic for Strongyloides stercoralis. Three of the four patients had adult T-cell leukemia, an aggressive neoplasm resulting from HTLV-I infection, while the other was an asymptomatic carrier of HTLV-I. Three of the patients had spent their childhoods in an endemic location for both organisms, suggesting an initial infection at that time. Three patients were symptomatic from their parasitism. We conclude that strongyloidiasis may be found in nonendemic locations in patients with either adult T-cell leukemia or an asymptomatic HTLV-I carrier state. Whether infestation with this parasite contributes to the leukemogenesis of HTLV-I, as postulated by others, cannot at this time be determined.

Aged↗
PubMed1989

Asymptomatic intrathoracic extramedullary hematopoiesis: a report of three cases.

Extramedullary hematopoiesis (EMH) is observed in people suffering from severe anemia of prolonged duration and appears to be a compensatory mechanism for disturbed medullary hematopoiesis. The hemoglobinopathies (such as thalassemia, spherocytosis, and sickle cell disease), neoplastic diseases such as leukemia and lymphoma, and others, including myelofibrosis and osteitis fibrosa cystica, are associated with EMH. These diseases and their resultant anemia have in common the ability to stimulate erythropoietin production, which in turn may stimulate hematopoiesis in organs of mesenchymal origin. The liver and spleen are the most common sites of EMH; however, other sites, including the falx cerebri, thoracic cavity, retroperitoneal area and pelvis have been reported. When present, intrathoracic EMH is most frequently associated with thalassemia. Spinal cord compression and hemothorax have also been reported as complications of intrathoracic EMH.

Adult↗
PubMed1989

Infection with the human T-lymphotropic virus type I. A review for clinicians.

The human T-cell lymphotropic virus type I (HTLV-I) is the first retrovirus identified in humans. It has been responsible for a number of clinical syndromes, most notably adult T-cell leukemia or lymphoma and tropical spastic paraparesis. In the United States, infection with this virus is most frequently found in specific subsets of our population, particularly in those who live in the southeastern states, have southern Japanese ancestry, or share intravenous drug paraphernalia. Understanding the epidemiology and clinical manifestations of this virus is necessary to properly diagnose and care for patients with HTLV-I infection.

HTLV-I Infections↗