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Biomedical subjects

A C Fleischer

Publications and source records attributed to A C Fleischer.

At least 127 records · Page 7Linked to original sources

Studies of blood flow employing duplex, pulsed Doppler real-time sonography.

The physics of pulsed Doppler techniques have been recently applied to clinical evaluation of superficial blood vessels and the flow within them. Essential physical principles of pulsed Doppler ultrasound are presented, including spectrum analysis and flow measurements. Duplex instrumentation combining high-resolution real-time imaging and a pulsed-Doppler system is described. Indications for duplex carotid sonography are outlined. Clinical applications are discussed and examples of normal and pathologic states are shown. Finally, the role of duplex sonography in the evaluation of carotid vascular disease is compared to traditional arteriographic and contemporary digital subtraction angiographic methods.

Blood Flow Velocity↗

Work in progress: ultrasonic texture of normal rat liver tissue using a standardized in vivo measurement.

A prototype computer-augmented diagnostic ultrasound system was used in an investigation of the range of echo amplitudes obtained from measurements of normal exteriorized rat livers. A secondary goal was to develop a method for minimizing variations in measurement techniques and instrument stability. The average echo amplitude was obtained from a user-selected homogeneous region of the liver on a B-mode scan image. A similar B-mode scan of a commercially available liver tissue equivalent phantom was also obtained immediately after each rat liver measurement and was used as a calibration scan. A normalization factor developed from the calibration scan was used to correct all in vivo measurements for system variation. The average echo amplitude from the livers of a group of normal rats, when corrected by the calibration scan, exhibited a narrow range of values with a coefficient of variation of only 5%. The development of a technique that yields a narrow range of values for normal tissues should encourage further investigation of tissue characterization methods.

Animals↗

Sonographic placental localization in the determination of the site of uterine incision for placenta previa.

The presence of a placenta previa is associated with increased maternal and fetal morbidity. Hemorrhage is considered the primary underlying factor contributing to this increased morbidity. Patients who have a placenta previa are often hypovolemic and are therefore at high risk for hemorrhagic shock if intraoperative blood loss during cesarean section is not minimized. The authors reviewed sonographic localization of the placenta prior to cesarean section for placenta previa, in order to facilitate proper selection of uterine incision based on placental site and so reduce intraoperative blood loss. Nineteen cases of placenta previa were reviewed. Seventeen patients underwent a conventional low cervical or classic incision, whereas two underwent paramedian uterine incision. Data from these cases suggest that in patients who wish to be sterilized and in whom the site of placental implantation is directly beneath the lower uterine segment, as well as extending to an area in which a traditional classic cesarean section would be made, a paramedian incisional technique is of value.

Adult↗

Sonographic evaluation of Peyronie disease.

In this case report we illustrate and discuss the use of high frequency, superficial organ, real-time ultrasound scanning in the evaluation of patients with Peyronie disease.

Adult↗

The role of sonography and the radiologist-ultrasonologist in the detection and follow-up of intracranial hemorrhage in the preterm neonate.

Intracranial hemorrhage (ICH), specifically hemorrhage in the subependymal germinal matrix, is a common disorder affecting preterm neonates. The authors discuss the relative virtues and limitations of portable, real-time ultrasonography (US) and computed tomography (CT) in detection and follow-up of sequelae of this disorder. The importance of cooperative effort on the part of the radiologist-ultrasonologist, neonatologist, pediatric neurologist, neurosurgeon and ultrasound technologist is emphasized.

Cerebral Hemorrhage↗

Hydrops fetalis: sonographic evaluation and clinical implications.

A systematic sonographic evaluation of hydropic fetus is presented, based on 21 cases and a literature review. The clinical implications of fetal ascites with or without anasarca, maternal hydramnios, maternal oligohydramnios, or an abnormally thick placenta are discussed as they relate to fetal outcome. It is concluded that sonography could play a major role in determining the optimal approach to perinatal management of the fetus in hydrops fetalis, and thus contribute to a reduction in the perinatal mortality and morbidity associated with this disorder.

Edema↗

Sonographic assessment of the bowel wall.

The thickness and regularity of the bowel wall can often be assessed by sonographic imaging. In 26 normal patients, the bowel wall averaged 3 mm in thickness when distended and 5 mm when nondistended. In contrast, in 12 patients with an abnormally thickened bowel wall, bowel wall thickness averaged 23 mm and the affected bowel segment exhibited decreased or absent peristalsis on real-time scanning. The data derived from this study may enable the sonographic distinction of abnormally thickened bowel wall from normal bowel segments in the collapsed and distended state.

Adenocarcinoma↗

Sonographic characteristics of congenital uterine abnormalities and associated pregnancy.

Faulty development of the mullerian duct system results in various uterine, vaginal, and renal abnormalities. Complete or partial absence of mullerian duct fusion and/or canalization results in septate, bicornuate, or double uterus; the specific anomaly depends upon the degree of fusion and canalization. Unilateral renal agenesis is frequently associated. Three cases of uterine anomalies associated with pregnancy are presented. When a pregnancy occurs in one side of a double uterus, the nonpregnant side may simulate a solid pelvic mass, such as a leiomyoma. In anomalies where there is a communication between two uterine cavities, the nonpregnant side may require the appearance of a cystic mass. Pregnancy associated with uterine anomalies carries significant morbidity.

Adult↗

Diagnosis of obstructive jaundice with nondilated bile ducts.

Obstructive jaundice with nondilated bile ducts was identified by percutaneous transhepatic cholangiography (PTC) in nine of 29 jaundiced patients in whom the etiology of the jaundice was not clearly established by clinical or laboratory means and no dilated ducts were seen at somography or computed tomography (CT). PTC was helpful in these none patients by: (1) differentiating obstructive from nonobstructive jaundice, (2) localizing the site and etiology of the obstructing lesion, and (3) determining operability.

Adenocarcinoma↗