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Biomedical subjects

A C Galizia

Publications and source records attributed to A C Galizia.

6 recordsLinked to original sources

Thrombotic thrombocytopenic purpura-like syndrome in the absence of schistocytes.

Thrombotic thrombocytopenic purpura is an uncommon disorder that if left untreated has a very high mortality. Schistocytes are generally considered essential for the diagnosis. A patient is presented with a thrombotic thrombocytopenic purpura-like syndrome in whom schistocytes were persistently absent and who responded to plasmapheresis.

Adult↗

Neuroleptic malignant syndrome and lithium carbonate.

The authors describe a case of neuroleptic malignant syndrome that occurred in a patient on amitriptyline and lithium carbonate. They suggest that lithium-antidepressant combination can precipitate this syndrome. Intestinal pseudo-obstruction was a prominent feature in the patient in this study.

Amitriptyline↗

Cerebral infarction in neuroleptic malignant syndrome.

Two young women with no risk factors for cerebrovascular disease developed hyperpyrexia, rigidity, and autonomic features while taking neuroleptic agents. The first presented with increasing rigidity, profuse diaphoresis and dehydration, and a right hemiparesis, and computed tomography (CT) showed a left striato-capsular infarction. The second became unresponsive following severe hypoxia and was found to have left-sided pyramidal signs three days later. Hemoconcentration and hypoxemia predispose to cerebral ischemic injury in the neuroleptic malignant syndrome and should be avoided as much as possible.

Adult↗