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Biomedical subjects

A C Iager

Publications and source records attributed to A C Iager.

5 recordsLinked to original sources

Defect symptoms and abnormal involuntary movement in schizophrenia.

Tardive dyskinesia (TD), a possible marker of the defect state of schizophrenia, was studied along with defect symptoms in 55 neuroleptic-treated chronic schizophrenic patients. Our cross-sectional data failed to replicate earlier findings of increased defect symptoms in TD patients (n = 14), except for more severe paucity of speech content when compared with non-TD patients (n = 41). Methodological issues that may account for some of the current and previously reported findings are discussed.

Adolescent↗

Treatment of schizophrenia with a vasopressin analogue.

Ten patients with chronic schizophrenia completed a 3-month double-blind, placebo-controlled trial with a vasopressin analogue. Modest improvement occurred, but several patients also experienced significant fluid and electrolyte imbalance.

Adolescent↗

A Negative Symptom Rating Scale.

Renewed interest in the role of negative symptoms in "defect state" schizophrenia calls for the design of a standardized, easy to use, reliable, and valid instrument to assess these aspects of psychopathology. In order to measure negative symptoms, we developed the Negative Symptom Rating Scale (NSRS). We report on the design, interrater reliability, and construct-validation of NSRS against the most frequently used negative symptom scales or subscales. In summary, the NSRS is a short, sensitive, highly specific, reliable, and apparently valid instrument for measuring negative symptoms in schizophrenia.

Adolescent↗