Biomedical subjects

A C Mancall

Publications and source records attributed to A C Mancall.

3 recordsLinked to original sources

PubMed1998

The buccal space: a doorway for percutaneous CT-guided biopsy of the parapharyngeal region.

We performed percutaneous CT-guided needle biopsies with a transfacial approach in the diagnosis of lesions of the parapharyngeal region. Via the buccal space, core needle biopsy specimens were obtained in eight patients with known parapharyngeal abnormalities identified by CT and/or MR imaging. In all cases, sufficient tissue was obtained to provide a definitive histologic diagnosis. There were no significant complications. This approach provides a reliable method for evaluation of parapharyngeal lesions.

Biopsy, Needle↗

PubMed1994

Experience with symptomatic spinal epidural cysts.

Epidural cysts, either synovial or ganglion, are an unusual cause of epidural compressive syndromes. We report a series of 26 patients with cysts, including 1 cervical, 2 thoracic, and 23 lumbar. Complaints at the time of admission and findings were similar to those associated with other epidural lesions at the same locations. The surgical technique is similar to that for other spinal lesions, with a wide exposure to enable a clear view of the cyst and surrounding structures, and is governed by imaging studies. Patients with cervical and thoracic lumbar cysts were free of symptoms and signs postoperatively. Of the 23 patients with lumbar cysts, 15 were free of symptoms after an operation, 7 had symptomatic improvement but had some pain and neurological findings, and 1 patient had no improvement. Computed tomography and magnetic resonance imaging permit accurate preoperative evaluation.

Adult↗

PubMed1985

The effect of delta-9-tetrahydrocannabinol on rat cerebrospinal fluid.

The effect of delta-9-tetrahydrocannabinol (THC) on cerebrospinal fluid (CSF) flow in rats was studied. The ventricular system of rats anesthetized with ketamine sulfate was cannulated via cisternal puncture, and CSF production was recorded. When administered in doses of 25 mg/kg to 45 mg/kg intraperitoneally, THC caused inhibition of CSF flow; in larger doses a smaller response was noted. In response to THC, CSF flow showed an initial drop, a return toward baseline, and a secondary decrease. It is postulated that this biphasic effect is due to a combination of THC's sympathomimetic effects on the CNS plus the local action that this drug has on choroidal synaptosomal neurotransmitters.

Animals↗