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Biomedical subjects

A C Santomauro

Publications and source records attributed to A C Santomauro.

4 recordsLinked to original sources

[Chronotropic and pressoric response in myocardiopathy in patients with heart failure during ergometric test. Correlation of spirometry variables with effort].

PURPOSE: To correlate the variables heart rate (HR), blood pressure (BP) and double product (DP) during the ergometric test with the variables oxygen consumption (VO2) and pulmonary ventilation (VE) of spiroergometry. METHODS: A study was carried out with 40 male patients suffering from cardiomyopathy with heart failure (functional class II-IV of NYHA)-of ischemic (IS), Chagas' disease (CH) and idiopathic (ID) etiology. These three groups were compared to a group of 10 normal individuals (N). The 4 groups were evaluated under 4 different conditions: rest (RES), anaerobic threshold (LA), power peak of exercise (P) and in the fourth minute recovery (REC). The investigation was carried out with the data obtained through spiroergometry (using a treadmill and spiroergometric equipment specific for the effort), as well as data related to HR, BP, DP, VO2 and VE. RESULTS: There were significant differences observed in the ergometric evaluate of the HR, BP and DP responses in the IS, CH and ID groups as compared with the N group. There were significant difference observed in the spirometric evaluation to the VO2 and VE efforts in the IS, CH and ID groups as compared with the N group. CONCLUSION: The HR, BP and DP variables studies, obtained by means of classic ergometry, unaided by direct methodology (spiroergometry) enabled them to infer valuable data for the control and evaluation of cardiomyopathies with IC, taking into consideration the low chronotropic and pressoric responses in the various phases of evaluation during this study, corresponding to the concomitant low performance of O2 consumption and pulmonary ventilation.

Adult↗

[Lymphocytic and serum magnesium in older healthy and hypertensive subjects].

PURPOSE: To study the lymphocyte and serum magnesium in older patients with and without arterial hypertension. PATIENTS AND METHODS: We studied the lymphocyte and serum Mg in 22 older patients, with diastolic blood pressure between 95 and 120 mmHg, not receiving drug treatment. A method of freezing produced total lysis of the cells. RESULTS: The mean lymphocyte Mg concentration in the older patients was 1.15 +/- 0.74 picomoles per 100 cells, significantly higher (p less than 0.05) than in the control group, that was 0.77 +/- 0.32 picomoles per 100 cells (lymphocyte Mg in older hypertensive patients/control = 1.49); there were no significant differences between groups with regard to serum Mg. Twelve older normotensive men studied also had lymphocyte Mg significantly higher than in the respective control group (lymphocyte Mg in older normotensive men/control = 1.70) and the serum Mg was also significantly higher than in the control group (1.63 +/- 0.12 versus 1.44 +/- 0.22 mEq/l. CONCLUSION: Since the high intracellular Mg concentration in the elderly patients may more accurately reflect the total body Mg status. We suggest to use Mg and Mg sparing diuretics in these patients, both hypertensive and normotensive, cautiously.

Aged↗

[Osteomyoarticular injuries in a physical conditioning program].

From the follow-up of one hundred and thirty patients in a physical conditioning program during the period of one year, partially disabling lesions with preliminary complaints were observed at the beginning of the program in thirteen patients, and lesions during the development of the program were observed in nineteen patients. Within the first group, four patients had to quit the program, two temporarily and two definitively. In the second group, five patients had to interrupt the program for periods varying from twenty days to two months. In both groups, treatment involving physical agents, kinesiotherapy and drugs was proposed. Interruptions in the physical conditioning program for periods longer than three weeks imply in considerable reduction of the cardiovascular benefits. The clinician must be aware of the fact that sedentary patients have not only cardiovascular, but also musculoskeletal deconditioning. These patients must be evaluated by the physiatrist in order that the disabling lesions be avoided and treated.

Adult↗