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Biomedical subjects

A Cabau

Publications and source records attributed to A Cabau.

14 recordsLinked to original sources

[Stress and premature menopause].

By acting on the neuroendocrine system during the stress response, life events may greatly affect homeostasis and favor the appearance of disease. Here, we describe a relationship between stressful life events and premature ovarian failure. From a mechanistic point of view, we suggest an autoimmune origin for such premature ovarian failure on the basis of the role of cytokines in folliculogenesis and of their increased production during stressful life events.

Adult↗

Effects of diethylstilbestrol (DES) medication during pregnancy: report from a symposium at the 10th international congress of ISPOG.

This article is a report based on presentations at the symposium Effects of Diethylstilbestrol (DES) Medication during Pregnancy at the conference Reproductive Life, 10th International Congress of The International Society of Psychosomatic Obstetrics and Gynaecology (ISPOG) in Stockholm, Sweden June 14-17, 1992. The objective of this symposium, chaired by Eylard van Hall and Ingar Palmlund, was to provide the basis for a discussion of how the risks of DES had been evaluated in different countries. In the general discussion following the presentations everybody present expressed concerns that DES might still be given to pregnant women in many parts of the world, called for measures to alert medical professionals world-wide to the hazards of the use of DES, and requested measures to effect an international ban of DES in medication for pregnant women.

Abnormalities, Drug-Induced↗

[Mourning and sterility].

The loss of a loved one, and particularly of a child, is beyond doubt a trauma which may disturb not only behavior, but also fertility. Bereavement may result in either the temporary loss of fertility or may, on the contrary, be followed by a long hoped-for and awaited conception. Both these situations are relatively commonly observed, but remain to be elucidated.

Adult↗

[The sterile woman, the physician and time. Number of spontaneous pregnancies in patients with functional sterility].

We analysed a one to eight year follow-up of the women remaining infertile after a double-blind study of cyclofenil versus placebo to determine the frequency of pregnancy occurring independently of treatment. Pregnancy occurred in 64 women, 25 during treatment, 39 without treatment. We evaluated the effect of age, cause and duration of infertility on the pregnancy rate. The cumulative pregnancy rates at 36 months after the beginning of the study was 92 per cent for anovulatory cycles, 55 per cent for luteal insufficiency, 69 per cent for cervical mucus insufficiency and 49 per cent for idiopathic infertility. Of the 213 women entering the study, pregnancy occurred in 111 women, 47 in 3 cycles by a placebo effect, 39 without any treatment and 25 during a cycle with treatment. We conclude that the rate of treatment-independent pregnancy is high among infertile couples and that the two main therapeutic factors are time and the doctor-patient relationship.

Adult↗

[Sterility from hormonal causes and unexplained sterility. Treatment with cyclofenil. Double-blind controlled study].

We treated 213 women during 3 cycles by cyclofenil versus placebo in a double-blind study. These women had infertility caused by ovulatory deficiencies, a cervical factor or idiopathic infertility. Twenty-six of the 114 women receiving cyclofenil became pregnant and 21 of the 99 receiving the placebo. The cumulative pregnancy rates were identical in the 2 groups: 22 per cent in 3 cycles. The authors insist on the importance of a good doctor-patient relationship and the role of the placebo effect in any treatment of infertility.

Adult↗

Monitoring of ovulation induction with human menopausal gonadotropin and human chorionic gonadotropin by ultrasound.

Ovarian follicular growth was monitored by ultrasound and plasma estradiol levels in 43 cycles of 27 patients. These women were treated with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) for anovulation or poor cervical mucus. Ultrasonography can help to prevent multiple pregnancies by allowing the withholding of the ovulatory injection of hCG if the number of mature follicles is too great. Nevertheless, mild to moderate hyperstimulation cannot always be prevented; it is sometimes the price one has to pay to obtain a pregnancy. Giving a direct view of follicular maturation, this method can be helpful in the determination of the best time for the induction of ovulation.

Chorionic Gonadotropin↗

[Secondary sterility].

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Abortion, Induced↗