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Biomedical subjects

A Caiazzo

Publications and source records attributed to A Caiazzo.

11 recordsLinked to original sources
PubMed2002

Dynamics and thermodynamics of the spherical frustrated Blume-Emery-Griffiths model.

We introduce a spherical version of the frustrated Blume-Emery-Griffiths model and solve exactly the statics and the Langevin dynamics for zero particle-particle interaction (K=0). In this case the model exhibits an equilibrium transition from a disordered to a spin glass phase, which is always continuous for nonzero temperature. The same phase diagram results from the study of the dynamics. Furthermore, we note the existence of a nonequilibrium time regime in a region of the disordered phase, characterized by aging, as occurs in the glassy phase. Due to a finite equilibration time, the system displays in this region the pattern of interrupted aging.

Journal Article↗
PubMed2000

Histologic response to intraligament injections using a computerized local anesthetic delivery system. A pilot study in mini-swine.

BACKGROUND: Intraligamentary (periodontal ligament) injection has been used to locally control pain with minimal anesthetic dose. The purpose of the present study was to determine the histologic effect of using a computer-controlled local anesthesia delivery system (CCLADS) for the administration of a periodontal ligament injection in the mini-swine model system. METHODS: Thirty-two sites in 3 mini-swine pigs with healthy periodontium were selected. Each site was notched on the mesial-lingual line angle of the tooth to allow a reference for needle placement and provide a histologic marker. An anesthetic cartridge was used with a 30-gauge needle attached to the handpiece of the CCLADS. This provided a controlled flow rate for 2 minutes. The control sites were treated with the same needle in place for 20 seconds. The animals were sacrificed and provided observation periods of 1 hour, 1, 4, 7, 21, and 49 days. Specimens were stained with hematoxylin and eosin and trichrome. RESULTS: Twenty-four hours after injection, limited localized inflammation was present. By 7 days, the ligament appeared within normal limits. Apical migration of the junctional epithelium extended to the apical limit of the notch and was similar in test and control specimens. CONCLUSIONS: Within the limits of this study, the histologic results showed that tissue responses following intraligament injections using a CCLADS demonstrated limited inflammatory responses within the first 24 hours, which abated by 7 days postinjection. Similar migration of the junctional epithelium was seen in test and control specimens and was probably related to tooth injury rather than anesthetic injections. Further investigations are warranted using CCLADS to determine whether clinical benefits will translate in the human model system.

Anesthesia, Dental↗
PubMed1999

Odontogenic sinusitis causing orbital cellulitis.

BACKGROUND: Odontogenic sinusitis is a well-recognized condition that usually is responsive to standard medical and surgical treatment. Current antibiotic therapy recommendations are directed against the usual odontogenic and sinus flora. CASE DESCRIPTION: The authors present a case of a patient with acute sinusitis initiated by a complicated tooth extraction that did not yield readily to standard treatment. The case was complicated by orbital extension of the sinusitis. The authors isolated methicillin-resistant Staphylococcus aureus, or MRSA, species from the affected sinus that usually is not encountered in uncomplicated acute nonnosocomial or odontogenic sinusitis. CLINICAL IMPLICATIONS: Though such forms of resistant microbial flora as MRSA are rare, they may be seen in patients who have a history of intravenous, or i.v., drug use and in immunocompromised patients. Management of patients with orbital extension of sinusitis requires hospitalization and i.v. antibiotic treatment.

Adult↗
PubMed1998

Lidocaine toxicity.

Local anesthetics are the most commonly used drugs in dentistry. The number of adverse reactions reported, particularly toxic reactions, are extraordinarily negligible. This article reports a case of lidocaine toxicity with its typical manifestation in a 37-yr-old healthy male. The toxic reaction followed transoral/transpharyngeal topical spraying of lidocaine preoperatively during preparation for general anesthesia. A review of dosages of the most commonly used local anesthetic drugs in dentistry and the management of a toxic reaction is presented. Clinicians need to be in a position to recognize and successfully manage this potential adverse reaction.

Administration, Topical↗
PubMed1997

[Quality of life after treatment in patients with laryngeal carcinoma].

Today laryngeal cancer can be cured by means of a variety of treatments (nearly 60% of the patients in an unselected population are still alive after 5 years). Despite the low incidence, this form of cancer can present a significant social problem because the form of treatment can have an impact on the esthetic, functional and emotional aspects affecting the quality of life (QOL). In the present study 690 laryngeal cancer patients treated with 6 different forms of therapy (total laryngectomy, partial laryngectomy, cordectomy, radiotherapy alone, total laryngectomy plus post-operative radiotherapy, partial laryngectomy plus post-operative radiotherapy) were asked to fill out a specific EORTC CORE QOL Questionnaire (EORTC QLQ C-30) as well as a specific head and neck questionnaire. Six multi-item function scales, 3 symptom scales and 6 individual items assessing both symptoms and economic consequences of the disease were evaluated. A total of 517 patients (74.92%) filled out the questionnaire. For each form of therapy the patients were divided by age (under and over 65 years of age). The results indicate that the quality of life is better in those patients who underwent a single form of treatment (i.e. radiotherapy alone, partial laryngectomy, total laryngectomy) than in those who underwent combination treatments (i.e. surgery plus radiotherapy). Moreover, the results were better in the older patients. Quite often laryngeal cancer patients are subject to psychosocial problems although this did not show up in the present study where the patients tended to consider surgery as a liberation. The social-cultural level of the patient has a significant effect on the quality of life as it proved better in those social classes were physical strength is of prime importance as opposed to those dominated by social parameters such as socialization, communication and aesthetics.

Aged↗
PubMed1984

[Characteristics of articular caps of the elbow in relation to flex-extension movement].

Considering the factors limiting flexo-extension movements of the elbow, particular importance has been given to the possible existing contact between its articular ends in the final stage of the movement. However, this factor has different importance according to the angle formed by the ulnar and humeral diaphysis with their respective epiphysis. Some authors assert that humeral and ulnar articular ends do not come into any contact during the first stage of the sigmoid cavity movement on the trochlea, according to their opinion, in fact, an angle of 45 degrees should exist between the prolongation of the humeral diaphysis axis and the lower epiphysis and the great ulnar sigmoid cavity should be oriented forward and high forming an axis that is inclined of 45 degrees the horizontal plane. In order to verify this affirmation, we have measured the width of these angles in 50 soaked humeri and 50 ulnas. The same angle has been measured in 50 radiograms of partially flexed laterally projected elbows. The mean observed values have been of about 34 degrees for the distal epiphysis-diaphysis angle in humeri and of about 25 degrees for the inclination angle of the orientation axis of the great ulnar sigmoid cavity. The results show that - when humeral epiphysis-diaphysis angle is larger or eventually equal to the ulnar one - it is sufficient that the considered angles are less than 45 degrees to get a correct and complete flexo-extension movement.

Cartilage, Articular↗