Biomedical subjects

A Cakan

Publications and source records attributed to A Cakan.

7 recordsLinked to original sources

PubMed2004

Sedation for fiberoptic bronchoscopy: fewer adverse cardiovascular effects with propofol than with midazolam.

OBJECTIVE: To study the influence of the sedatives propofol and midazolam on cardiovascular parameters in patients undergoing fiberoptic bronchoscopy (FOB). METHODS: 100 patients without a history of cardiac disease undergoing diagnostic FOB were investigated in a prospective-randomized design. After premedication with intramuscular atropine (0.01 mg/kg BW) patients received sedation with either propofol (group P, n = 50) or midazolam (group M, n = 50). Heart rate, arterial oxygen saturation (psaO (2)) and non-invasive blood pressure were recorded prior to and immediately after induction of sedation, when at the level of vocal cords, during the interventional diagnostic procedure (IDP) and 15 min after the end of the FOB. RESULTS: The mean heart rate and systolic pressure were significantly lower in group P when compared with group M when at the level of vocal cords and during the IDP (p < 0.05). The total incidence of major arrhythmias was 10 % and the incidence of minor arrhythmias was 62 %. A decline in psaO (2) < 90 % occurred in 16 patients of group M and 5 patients of group P (p = 0.44). CONCLUSION: Propofol, when used as a sedative for FOB, is associated with lower hemodynamic side effects than in patients undergoing FOB with midazolam. In addition, it is well-tolerated by patients with pre-existing pulmonary disease. Even patients without a history of heart disease should be monitored for cardiac arrhythmia while undergoing FOB for pulmonary disease, especially patients with a FEV (1) of less than 50 % of the predicted value.

Anesthetics, Intravenous↗

PubMed2004

The histological effect of harmonic scalpel and electrocautery in lung resections. An experimental study in a rat model.

AIM: In the last decade, ultrasonically activated scalpels (the Harmonic Scalpel, HS) have been developed and used for both open and endoscopic surgical procedures. The present study compares the deepness of lung tissue damage caused by HS and unipolar electrocautery (EC) in rats. METHODS: Ten rats were used for the study. Morphological damage on lung parenchyma of the rats was measured with the ocular micrometer in light microscopy. RESULTS: The mean depth of the tissue damage was 0.23+/-0.08 mm in the HS group, and 0.33+/-0.10 mm in the EC group. The difference was statistically significant between the 2 groups (p=0.028). CONCLUSION: HS induces significantly less tissue damage than EC in rat lungs.

Animals↗

PubMed2001

Atypically located pericardial cysts.

Pericardial cysts are generally recognized when they present in a cardiophrenic angle, but may not be suspected when they occur elsewhere in the thorax. To highlight the unusual localisations of pericardial cysts, we represent two patients with cysts of which one was adjacent to the left pulmonary hilum and the other was located in the subpulmonary region. The clinicians should take into consideration this entity in the differential diagnosis of cystic lesions of the mediastinum.

Adult↗

PubMed2001

[Thoracic trauma: analysis of 987 cases].

In Izmir Chest Diseases and Thoracic Surgery Training Hospital, Department of 1st Thoracic Surgery, between 1988 and 1998, 987 patients who were treated for their chest trauma were retrospectively reviewed in regard to their age, sex, cause of trauma, associated organ injuries, treatment modality, complication rate and mortality. In 710 (72%) cases of chest injuries were related to blunt trauma and 277 (28%) patients sustained penetrating trauma. 402 (41%) patients underwent tube thoracostomy only. While majority of patients (553 pts, 56%) were managed conservatively, only 32 (3%) underwent thoracotomy. Complication rate in our series was 4.6% and the most frequently atelectasis was seen. 13 patients died due to trauma related causes (mortality: 1.3%). There was no difference between blunt and penetrating trauma patients in view of morbidity and mortality rates (p = 0.29 and p = 0.10, respectively). Mean hospital stay among all patients was 9.6 +/- 8.6 days. This period was 10.0 +/- 8.5 days in blunt trauma group, and 8.4 +/- 8.6 days in penetrating trauma group. However this difference has reached statistical significance at a p value of 0.0068.

Adolescent↗

PubMed2001

Tuberculosis of oral mucosa.

In secondary tuberculosis, lesions of the oral cavity may accompany lesions of the pharynx, lungs, lymph nodes or miliary tuberculosis. A 35-year-old male was suffering from swelling of his right cheek, cough, weakness and weight loss. There were local hyperemia and irregular oral mucous in the inner part of the right cheek. Chest x-ray showed bilateral nodular opacifications and a cavity of 2 cm. Acid-fast bacteria were present in sputum and Lowenstein-Jensen culture was positive. The pathological signs of the biopsy taken from the buccal mucosa including multistratified squamous epithelium were: tubercle structure, Langhans' giant cells and minimal cazeation necrosis. After anti-tuberculous chemotherapy oral and pulmonary lesions were almost in remission. Following this case report of lung tuberculosis accompanied by tuberculosis of oral mucosa, the literature related is reviewed.

Adult↗

PubMed2000

[Tracheobronchial injuries due to blunt thoracic trauma: 10 years experience].

The tracheobronchial injuries are seldom, but life threatening. Their successful diagnosis and treatment require a high level of suspicion. In this report, we reviewed our experience with seven patients with tracheobronchial injuries due to blunt thoracic trauma, treated over the past 10 years. Definitive diagnosis was recognized with bronchoscopy after clinical suspicion. Most injuries were located in the right bronchial tree (five patients), whereas only one patient had an injury located in the left bronchial tree and one in trachea. The majority of the injuries were repaired primarily (five patients) and two required lobectomy. There were no postoperative mortality; but three postoperative complications were noted; one empyema and two partial stenoses on the repair line.

Adolescent↗

PubMed1998

Autologous blood patch pleurodesis in spontaneous pneumothorax with persistent air leak.

In a prospective study series of 167 patients with tube thoracostomy for spontaneous pneumothorax in 1993-1996, 32 patients (age range 16-79 years, mean age 45.5 years) were treated with autologous blood-patch pleurodesis for persistent air leak. In 27 (84%) of cases the air leak ceased within 72 h after the pleurodesis. The duration of air leak was significantly shorter (p < 0.01) than in simple drainage. Empyema developed in three cases, and two patients with failed pleurodesis required open thoracotomy. Minor complications, mainly fever and pleural effusion, occurred in nine patients. Neither analgesia nor sedation was required during or after pleurodesis. There was no recurrence of pneumothorax during 12-48 months of observation, whereas simple drainage was followed by recurrence in 22 patients. Blood-patch pleurodesis is a simple, effective and painless method in pneumothorax, but carries an increased risk of intrathoracic infection.

Adolescent↗