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Biomedical subjects

A Callis

Publications and source records attributed to A Callis.

4 recordsLinked to original sources
PubMed1991

Activity of citrulline malate on acid-base balance and blood ammonia and amino acid levels. Study in the animal and in man.

An experimental evaluation of citrulline malate (Stimol, CAS 54940-97-5), an anti-fatigue compound, was undertaken in man and in the animal in order to study the pharmacological activity of the substance at hepatic and renal level. In man, the protocol involved a double-blind randomized, placebo-controlled cross-over technique. The study in the animal was blind and placebo-controlled with two randomized parallel groups. Results showed that citrulline malate stimulates hepatic ureogenesis and favorizes the renal reabsorption of bicarbonates. These metabolic actions had a protective effect against acidosis and ammonia poisoning and explain the anti-fatigue properties of citrulline malate in man.

Acid-Base Equilibrium↗
PubMed1975

2,3-2, 3-.

Erythrocityc variations of glycolytic intermediates and 2,3-DPG levels in rabbits performing strenuous exercise under hypoxic conditions are correlated with blood pH variations. The hypoxia alone is not able to induce directly an increase of erythrocytic 2,3-DPG level which would facilitate tissue oxygenation.

Animals↗
PubMedDate not supplied

[Measurement of differences in oxygen between arteries and veins. Application to the study of cerebral metabolism].

The cerebral metabolic exploration requires a precises measurement of the arterio-venous differences and this, for each metabolite. As far as oxygen is concerned, there are many techniques to measure the blood contents (CaO2 - CvO2). Direct methods give accurate results but their high technicality makes it difficult to adapt them to the increasing medical demand. The authors report the principle and the technique of the indirect method based upon the measurement of the total hemoglobin concentration and the saturation in oxygen. They recall the possible causes of errors, the main of which - induced by an insufficient homogenization of the sample - is (by the way) to be found in both groups of methods although to a lesser degree in the indirect method. Therefore, the latter, that all normally equipped laboratories can carry into practice, seems quite adapted to the "hospital demand" and its validity confirmed by an experience that now belongs to the past.

Arteries↗