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Biomedical subjects

A Castaigne

Publications and source records attributed to A Castaigne.

At least 181 records · Page 10Linked to original sources
PubMed1979

[Acute mitral incompetence of ischemic origin (author's transl)].

Clinical findings and results of treatment in 17 patients with acute mitral incompetence are described. The lesions were secondary to a recent myocardial necrosis causing severe cardiac failure (shock, or acute left ventricular failure), and the presence of mitral incompetence was confirmed by right catherization (15 cases) and/or left ventricular angiography (13 cases). The anatomical lesions are described in 14 cases: rupture of the posterior mitral papillary muscle in 7 cases, and acute dysfunction of the muscle in 7 other cases. Eight patients were treated by an intra-aortic balloon to assist circulation, and 14 were given vasodilators (phentolamine, trinitrin) associated in 5 cases with positive inotropic drugs. Surgical treatment was given (mitral valve replacement) in 7 cases. The respective effects of vasodilators and circulatory assistance are discussed, as well as the indications for, and results of urgent surgical treatment (6 successes in 7 operations).

Acute Disease↗
PubMed1978

[Vasodilator treatment of the acute phase of myocardial infarct with phentolamine. Analysis of hemodynamic results and therapeutic indications].

Treatment by phentolamine was carried out in 30 patients presenting with an acute myocardial infarction complicated by left ventricular failure, 8 of which had cardiogenic shock. The response to treatment was closely related to the level of overload of the left ventricle. Significant improvement in the haemodynamic state was only observed in the most severe cases of cardiac failure, and in these cases was accompanied by only a minimal and insignificant change in mean arterial pressure and heart rate.

Acute Disease↗
PubMed1977

[The aged heart in surgery].

The risk of surgical operation is increased by the presence of heart disease. The statistics are too limited for this risk to be expressed more precisely. The heart in the elderly is no longer a normal heart. The myocardial functional reserve declines, the quality of the A.V. conduction is not always good and vascular fibrosis progresses. Surgical operation thus increases the risk of a cardio-vascular accident. One should distinguish the risk due simply to old age. The existence of known heart disease often leads to heart failure which is difficult to treat. The great risk of surgical operation is then the risk of overloading the heart. In the absence of known heart disease, one should beware of latent coronary insufficiency. The major risk is then hypoxia. The special problem of degenerative A.V. conduction disorders may require the insertion of a pace-maker. Pre-opératoire cardio-vascular assessment is thus necessary in the elderly subject. It should, however, remain simple. Careful history and auscultation, verification of the periphéral arteries, chest XRay and E.C.G.

Adaptation, Physiological↗