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Biomedical subjects

A Cession-Fossion

Publications and source records attributed to A Cession-Fossion.

At least 19 recordsLinked to original sources

[Effect of pindolol on tachycardia and certain metabolic variations dependent of muscular exertion].

1. -- In young well trained adults, adrenergic beta receptors blockade by pindolol or propranolol causes a relative bradycardia during running on a threadmill during 10 to 20 min at 50% VO2 max. 2. -- Pindolol activity is maximum for 5-7.5 mg ingested one hour before starting. In two subjects, tachycardia reappears for 30 mg : this secondary increase may be explained by an intrinsic sympathetic activity of pindolol. 3. -- Propranolol is about 14 times less active than pindolol without any intrinsic sympathetic activity.

Adult

[Urinary catecholamine excretion in aging].

In ageing female subjects, the urinary noradrenaline excretion (UNA) is reduced with respect to the controls in young adults. On the other hand the ratio UNA/clearance of endogenous creatinine increases with ageing. This provides a confirmation of the fact that ageing is associated with an increase in plasma noradrenaline. The ratio UA/clearance of creatinine remains unaltered. So far the physiological meaning of these results remains unclear.

Adult

[Effect of horizontal immersion into water at 38 degrees C on the urinary elimination of catecholamines].

The urinary excretion of noradrenaline, adrenaline and creatinine has been studied in normal young individuals during a water bath at 38 degrees C for 40 minutes. The noradrenalinuria and the ratio noradrenalinuria/creatininuria are decreased, indicating an inhibition of the vasomotor activity of the orthosympathetic system. This inhibition is related to the consequence of the external hydrostatic pressure of the water filling the intrathoracic venous reservoirs and increasing the systemic blood pressure at the sino-baroreceptor level, hyperthermia playing a very limited role.

Adult

[Orthosympathetic reaction during paroxysmal asphyxia in the rat].

Acute hypercapnic hypoxia provoked by the ligature of the trachea kills the rat in 3 to 5 minutes. Catecholaminemia is immediately increased by adrenaline release from the adrenal medulla for the largest part. Catecholamine contents of the suprarenal glands is not decreased at the time of death.

Adrenal Glands

[Influence of sauna baths on urinary excretion of catecholamines].

The urinary excretion of noradrenaline, adrenaline and creatinine has been studied in 22 normal young men during a sauna bath (20 minutes). The radio noradrenalinuria/creatinine is specifically increased, indicating a stimulation of the orthosympathetic system (19.6 ng.mg-1 +/- 7.9 in basal state; 30.5 +/- 15.7 in sauna bath).

Adolescent