[Colonic vascular malformations].
Explore the source record for details and available documents.
Blood Vessels↗
Biomedical subjects
A Charneau
Publications and source records attributed to A Charneau.
[Resolution of scleroderma renal crisis with thrombotic microangiopathy. Case report (author's transl)].
Renal involvement is a common cause of death in patients with systemic sclerosis (diffuse scleroderma). The poor prognosis is due to malignant hypertension and rapid deterioration of renal function. Therefore bilateral nephrectomy followed by hemodialysis and transplantation are proposed to avoid fatal outcome. The authors describe the case of a 37 year-old male suffering from diffuse scleroderma, and who developed malignant hypertension and renal failure. The renal biopsy and biological investigations showed thrombotic microangiopathy. The plasma renin activity was in a very high range. Control of hypertension and improvement of renal function were obtained by major antihypertensive drugs, i.e. intra-muscular clonidine, propranolol and dihydralazine. 14 months later, plasma creatinine is 2 mg/100 ml and blood pressure is 140/80 mm Hg. This case and similar ones reviewed in the literature demonstrate that bilateral nephrectomy should be performed in "scleroderma renal crisis" only after failure of very potent antihypertensive therapy.
Adult↗
[Angiodysplasia of the right colon: a frequent cause of lower digestive tract hemorrhage. Apropos of 13 cases].
13 observations of right hemorrhagic colic angiodysplasia were detected in less than 5 years: 9 times with proctorrhagia of varying amounts, 4 times with an endoscopic aetiological evaluation of iron deficiency anemia. Colonoscopy revealed lesions in 11 patients out of 13 in the form of erythematous spots of vascular hemorrhagic appearance in 5 cases. The arteriography was positive in 5 of the 7 cases where it was performed. Treatment was endoscopic 6 times, by follow-up electrocoagulation, 2 times, by right hemicolectomy. The latter was carried out immediately in 2 other cases. In 5 cases, iron treatment was all that was necessary. These right colic angiodysplasias are often an unknown cause of digestive hemorrhage or iron deficiency anemia. The difficult diagnosis depends on the colonoscopy performed by an operator accustomed to this type of lesion. It is carried out in emergency in cases of acute bleeding. Sometimes an arteriography is also performed. Endoscopic treatment may be an alternative to standard surgical treatment in elderly high-risk patients.
Aged↗