Biomedical subjects

A Chlihi

Publications and source records attributed to A Chlihi.

8 recordsLinked to original sources

PubMed2006

[Intertoe space cutaneous epidermoid carcinoma].

BACKGROUND: Localisation of epidermoid carcinoma in the intertoe space is very rare. We report a case occurring in a setting of chronic intertoe intertrigo. CASE: A 66 year-old woman presenting intertoe intertrigo for 30 years consulted for painful ulceration of the 3rd intertoe space of the left foot present for 4 years and refractory to antifungal treatment. The examination revealed ulceration with infiltrated edges occupying the entire 3rd intertoe space, with no satellite adenopathy. Histological examination of the skin biopsy sample revealed epidermoid carcinoma. Wide excision of the lesion was performed with a safety margin of 5 mm, with removal of the 3rd and 4th left toes. The outcome was favourable with no relapse after 12 months. DISCUSSION: A single publication reported a series of 22 cases of intertoe epidermoid carcinoma in which the key aetiological feature of tumour was continual maceration. In this patient, maceration was maintained by a number of factors, including cultural factors: ritual ablutions performed 5 times daily, with no drying of the intertoe spaces, and domestic cleaning involving large quantities of water several times weekly.

Aged↗

PubMed2002

[The use of preputial skin as cutaneous graft after circumcision. Report of 30 clinical cases].

Through a study of 30 clinical cases, collected at the service center of plastic surgery and burns in Averroes University hospital at Casablanca, the authors underline the interest of using preputial skin as full-thickness skin graft for the treatment of burns and their sequelaes in non-circumcised boys, whose age ranged from one to four years. At this age, they are more exposed to domestic accidents. The preputial skin graft gives the advantage of the absence of scare prejudice at the donor site each time the circumcision is possible; and provides a skin of good elastic quality avoiding secondary retraction with a very favorable rate of graft intake. Although the application of this technique for other affections is possible, but remains limited by the hyperpigmentation of the graft.

Burns↗

PubMed2002

[The Marjolin's ulcer, destiny of a unstable scar. About 54 cases of burn's sequelae].

Through a study of 54 cases of malignant transformation on burn's scar, collected during a period of 8 years, the authors underline the particularities of this tumor, reported at the literature such as the preponderance of spinocellular carcinoma as histological type, the high rate of lymphatic metastasis and recurrence, and also the poor prognosis. In addition, the authors underline the non-rare character of this affection, whose incidence is correlated to the level of medication; it's occurring in younger patients, and its short delay of transformation. The treatment is based on prevention by a correct management of the initial burns, the cure of any instable scar, and a regular surveillance. The biopsy should be realised in case of suspicion of degeneration. The radical treatment must be initially aggressive, consisting on large excision associated eventually to radiotherapy. This treatment must be integrated in an elaborating therapeutic strategy, taking on consideration the evolutive potentiality of these tumors in order to improve chances of recovery and survival.

Adolescent↗

PubMed2000

[Air tissue expansion, as an alternative to physiologic serum expansion: report of 30 cases].

There has been a renewed interest in cutaneous expansion as a plastic surgery procedure. Complications and failures remain considerable despite a more adequate and standardized technique. Based on a study of 30 cases of cutaneous expansion for burns sequelae, the authors emphasize the value of using air instead of physiological saline as filling medium, to reduce the negative repercussions on quality and quantity of cutaneous gain, related to the increasing weight of the prosthesis, even for large and possibly repeated expansion volumes.

Adolescent↗

PubMed1995

[Fatal hepatic necrosis during treatment with sodium valproate].

The authors report a case of fatal hepatic failure in a 19-year old young man suffering from absence seizures and treated for two months with valproic acid (VPA). The duration of VPA therapy before onset of clinical manifestations was four weeks. The prodromal symptoms were weakness, anorexia, and vomiting, then in a few weeks occurred a jaundice and an hepatic encephalopathy leading to death. Among laboratory findings disturbance of liver tests and particularly depressed levels of clotting factors were observed. The histologic study of the liver showed an extended centrolobular necrosis associated with fatty change and fibrosis. The mechanism of this hepatic failure remains unknown. The seriousness of this complication necessitates to respect any contraindications.

Adult↗

PubMed1995

[Scrotal reconstruction after necrotizing cellulitis of the perineum and external genital organs. Apropos of 21 cases].

The author report twenty one cases of tissue reconstruction defects secondary to necrotizing cellulitis of perineum and external genital organs, treated at the burns and plastic surgery unit of CHU Ibn Rochd of Casablanca, between 1992 and 1994. Depending on the extent of the defect, the techniques used were gracilis musculocutaneous flap in 8 cases, thigh fasciocutaneous flap in 7 cases, groin flap in 4 cases, simple skin sutures and skin grafts in one case, respectively. The morphological results were satisfactory. The mean hospital stay after reconstruction was 15 days.

Adult↗

PubMed1993

[Preventive treatment of hemodynamic disorders during conventional spinal anesthesia].

The prevention of blood pressure fall during a conventional spinal anaesthesia effected with 20 mg (4 ml) of isobaric 0.5 p. 100 bupivacaine relies on the use of vascular filling and/or a vasoconstrictor. A randomized prospective study was performed to evaluate the comparative efficacy of these two treatments. 148 patients were included and divided into three groups. Group I (n = 50): 2.5 mg IV bolus of etilefrine followed by continuous infusion (0.35 mg.kg-1.h-1). Group II (n = 50): 30 ml.kg-1 infusion of saline isotonic solution for 90 min, with infusion rate according to blood pressure. Group III (n = 48) did not receive any preventive treatment. A blood pressure fall of more than 30% of the initial value was observed in 59 patients: 18% of the etilefrine group, 28% of the saline infusion group, 54% of the control group. This peculiar frequency of hypotension in the control group emphasizes the need of a preventive treatment. Haemodynamic changes were fewer and less important in the etilefrine group compared with the saline infusion group. No failure and a better tolerance in the vasoconstrictor group were also to be noticed. These clinical data suggest that etilefrine could meet satisfactorily the therapeutic requirements.

Anesthesia, Spinal↗

PubMedDate not supplied

[Cancer of the rectum in young adults. Apropos of 38 cases].

This retrospective study is based upon 38 cases of rectal carcinomas occurring in young individuals aged under 25, collected during the 15 year period from January 1978 to December 1993. The mean age of the patients was 23 (range: 14 to 25), with a gender ratio of 2.1. Histology revealed a well differentiated adenocarcinoma in 12 cases, a moderately or slightly differentiated and undifferentiated carcinoma in 14 cases, a colloid carcinoma in 10 cases and a villous tumor with malignant change in 2 cases. Curative surgical excision was possible in only 11 patients. Sixteen patients underwent a palliative procedure, while 12 refused surgery. No treatment was proposed to 3 patients with visceral metastases. Only 11 patients could be followed up, with a mean 5-year survival rate of 10%. The prognosis of rectal carcinoma in young individuals is poor because of late diagnosis at an advanced stage and the aggressive histologic forms encountered.

Adenocarcinoma↗