Biomedical subjects
A Chouchane
Publications and source records attributed to A Chouchane.
Polio outbreak in Algeria: epidemiological, virological and vaccinational aspects.
During a poliomyelitis outbreak (October 1983) in El Oued territory (Algeria) 28 cases were diagnosed. All the patients were under 4 years old. The ratio of females to males was 0.33. No deaths occurred during this epidemic. 25 of the 28 polio cases were diagnosed by cell culture and 81% were polio type 1. The epidemiological survey established that the epidemic was due to the insufficiency of vaccination coverage, since the consumption of antipolio vaccine in the epidemic area had dropped by 25% from 1982 to 1983. 7 of the 28 polio cases had been given at least 3 injections of vaccine at the correct intervals. 5 of 8 vaccine samples from the epidemic area had an insufficient titre of polio type 1. These observations showed that the nature of the vaccine, whether killed or live virus, was less important for controlling poliomyelitis than providing medical and sanitary facilities to ensure good vaccination coverage.
[Rheumatic manifestations of Gougerot-Houwers-Sjögren syndrome].
The authors retrospectively survey the concept of the Gougerot-Houwers-5jögren syndrome which links articular disease with the "dry" syndrome (pharyngitis sicca) and then go on to study the rheumatic conditions found in the Gougerot-Houwers-Sjögren syndrome. They point out that the association between the "dry" syndrome and rheumatic appearances varies in frequency according as whether the problem is seen from a rheumatological, dermatological, ophthalmological or stomatological point of view. They establish the frequency of the various rheumatic conditions, stressing the importance of the association with rheumatoid polyarthritis. They study the associated biological and visceral backgrounds, the thyroid, renal, digestive, blood, neural, allergic and immunological conditions and describe the rheumatic appearances of the other collagenoses associated with the "dry" syndrome. They conclude with the current difficulty of restricting the scope of the Gougerot-Houwers-Sjögren syndrome when histological and scintigraphic techniques have broadened it. They would like to see exact criteria adopted to define this syndrome.