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Biomedical subjects

A Cicigoi

Publications and source records attributed to A Cicigoi.

11 recordsLinked to original sources
PubMed1991

[Seminal duct abnormalities in cryptorchism: our experience with 334 cases].

Undescended testis is one of the most common anomalies in pediatric age; despite numerous theories offered to explain its etiology, the true mechanism of the anomaly seems not to have been fully elucidated. The purpose of this prospective study was to investigate the incidence of epididymal abnormalities in undescended testes, the potential role of these anomalies in testicular descent and in incidental infertility. All patients were submitted to orchidopexy during which the complete anatomical situation of the epididymis and vas deferens was detected. In a group of 334 testes the incidence of congenital defects was 68%. The severity of these abnormalities appeared to be strictly correlated to the level of undescended testis. The incidence was 85% when the testis was in the abdomen, 82% when in the inguinal canal, 63% when next to the external inguinal ring and 53% when the testis was ectopic. The epididymal detachment at the head was the most common anomaly (113 cases), followed by extended epididymis (91 cases) and by total detachment of epididymis from the testis (70 cases).

Abnormalities, Multiple↗
PubMed1991

[Early diagnosis and correct treatment of varicocele in puberty].

Varicocele normally presents itself in adolescence, with an incidence of 16 per cent. Less than one third of the boys, though, will suffer from male infertility in adulthood. Therefore, it seems excessive as well as imprudent to suggest surgery to all those patients. We worked out some parameters to identify "risky" cases of varicocele. From June to November 1990 we studied 45 patients from 10 to 16 years of age affected by varicocele, taking into consideration the following factors: puberal phase, symptomatology, degree of varicocele, testicular volume, Doppler ultrasound, hormonal profile. A Doppler ultrasound test evidenced a clinically undetected right reflux, in addition to a left varicocele, in 13 patients (34.4%). Sixty per cent of these 13 patients revealed a pathological response to LHRH test; this incidence is very close to that evidence in clinical bilateral varicocele. We believe that a right reflux showed by ultrasounds, represents a cause of further alteration in the patient's endocrinological balance in addition to increasing his risk of infertility. Purpose of this study was to draw a guideline for early diagnosis, correct treatment and follow-up of varicocele in peripubertal age.

Adolescent↗
PubMed1986

[Blood and urinary values of CEA and CA 19-9 in patients with bladder carcinoma].

Carcinoembryonic antigen (CEA) and Ca 19-9 levels in urine and serum from 46 patients with bladder cancer in varying stages have been evaluated. All samples of urine were obtained germ-free and without bacterial infection in the bladder. The sensitivity of CEA monoclonal antibody is 60.8% and specificity is 80%. Ca 19-9 test has higher sensitivity (74%) and the same specificity. Correlation between staging, grading and CEA or Ca 19-9 values were also evaluated.

Adult↗
PubMedDate not supplied

Tumor markers (CEA, TPA and CA 19-9) in urine of bladder cancer patients.

This study was carried out to evaluate the usefulness of determining urinary levels of carcinoembryogenic antigen (CEA), tissue-polypeptide antigen (TPA), and gastro-intestinal cancer antigen (Ca19-9) in addition to the usual diagnostic procedures for bladder cancer. Sixty-seven patients with transitional bladder cancer, 40 healthy controls and 20 patients with inflammatory diseases of the urinary tract were considered. All urine samples were obtained from patients with intact renal function and no urinary tract infection. TPA and Ca19-9 urinary levels in patients with G3 bladder tumors were significantly higher than in those with lower graded neoplasms. The sensitivity, specificity, and predictive value of a positive (PV+) or negative (PV-) test and the diagnostic accuracy were also evaluated. Ca19-9 was the best urinary marker for bladder cancer (sensitivity 71.6%, specificity 91.6%, PV+ 90.5%, PV- 74.3%, diagnostic accuracy 81%).

Adult↗