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Biomedical subjects

A Cioltei

Publications and source records attributed to A Cioltei.

13 recordsLinked to original sources

Nodular salpingitis and tubal endometriosis. I. Comparative clinical study.

Nodular salpingitis and tubal endometriosis have been referred to in succession as salpingiosis, diverticulosis, adenomyosis of the oviduct, endometrioid conditions, etc. This varied terminology underscores their etiopathogenetic and morphological substratum which is different from that of non specific tubal inflammation, but at the same time this variety of terms has always created confusion in interpretation and diagnosis. We have considered it necessary to carry out a comparative study of nodular salpingitis and tubal endometriosis in 42 cases of sterility operated during the last two years for tubal obstruction and in which histological examination has yielded evidence for the lesions of nodular salpingitis (NS) or endometriosis (EM) in at least one of the oviducts. As for the etiology of the two diseases, we have discussed the role plaid by inflammatory conditions, uterine trauma (curettage) and dystrophic disorders, as well as the importance of hyperandrogenism in NS. Taking into account the diffuse sclerogenic tendency of the tubal wall in NS and the concomitant inflammatory and dystrophic lesions in the peritubal tissues in EM, the postoperative outlook depends on early surgery, to be performed before tubal anatomy has been completely altered.

Adult

Nodular salpingitis and tubal endometriosis. II. Diagnosis and differential diagnosis.

Nodular salpingitis and tubal endometriosis are dystrophic disorders (salpingioses) the clinical importance of which is mainly due to their interference with female fertility. We have studied 42 cases of women operated for tubal sterility, viz. 23 cases of nodular salpingitis (NS), 17 of endometriosis (EM) and two cases in which both lesions were present. Pre-operative x-ray and celioscopic exploration was performed in order to assess the severity of the lesions and the outlook after tubal plastic surgery. X-ray examination reveals the diverticular nature of these lesions. Both diseases may be localized in any of the tubal segments. The postoperative prognosis depends on early surgery, site of the lesion and its nature.

Adult

The treatment with 2-brom-alfa ergocriptine in the syndrome amenorrhea-galactorrhea.

In this study, the authors present the results obtained in thirteen cases with amenorrhea-galactorrhea treated with 2-brom-alfa-ergocriptine in which the menstruation has reoccurred in eleven patients, three of them becoming pregnant. The authors have accurately described the evolution of the three pregnancies, which were delivered at term and the children born were normal. The present study was elaborated in the Sterility Department of the Clinic of Obstetrics and Gynecology "Giulesti", University School of Medicine, Bucharest. The study refers to the use of 2-brom-alfa-ergocriptine (Parlodel-Sandoz) in the treatment of the amenorrhea-galactorrhea syndrome associated with sterility.

Adult

Three women with 45,X/46,XX mosaic and multiple spontaneous abortions.

One hundred couples in whom the females had experienced multiple spontaneous abortions were studied. In this series three women with 45, X/46,XX were observed. The paper discusses the significance of this observation pointing out to the fact that these women run an increased risk of abortion of giving birth to babies with Turner's syndrome.

Abortion, Habitual

De novo balanced translocation: 46, XX, t(13;20)(q34;p 11).

The authors present a family in which the father has brachymetacarpy and brachymetatarsy and the mother has a 13/20 translocation. A baby was born with multiple malformations similar to the trisomy syndrome for the short arms of chromosome 20. The genetic consequences of the translocation are discussed.

Chromosome Aberrations

The timing of ovulation by a method of direct basophil cells count.

The variation of the basophil cells number during the menstrual cycle was studied by the method of Shelley and Parnes, slightly modified. The study comprised 29 women diagnosed as primary or secondary amenorrhoea (first group) and 38 women with normal menstrual cycle, twenty of them being fertile and 18 diagnosed as secodary sterility (second group), including also two women in the second month of pregnancy. The radioimmunological measurement of luteinizing (LH) and follicle-stimulating (FSH) hormone was applied for the second group. The data obtained on 34 women of the second group showed the precipitous decrease of the number of basophils from the level of 20--50/mm3 in the follicular phase, or even their disappearance. This decrease corresponded to the LH increase. Moreover, the morphologic examination of the basophils during the menstrual cycle allowed to classify these cells into three categories: intact, partially degranulated, and firing, the number of the latter type increasing on the day of ovulation at the expense of the first two types.

Adult