[Hypothyroidism secondary to prolonged treatment with lithium carbonate].
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Biomedical subjects
Publications and source records attributed to A Coca.
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We present a case of pulmonary alveolar microlithiasis with an unusual radiological pattern in an an otherwise asymptomatic young woman. It was characterized by a reticulonodular pattern predominantly in the lower lung fields with Kerley B lines. The diagnosis was made by transbronchial lung biopsy. We found an otherwise asymptomatic brother with the same radiological pattern.
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The case histories of 1200 patients admitted to our hospital over a 20 month period were reviewed to determine the degree, frequency and cause of dissociated cholestasis as a biological syndrome. Patients were divided into two groups: group I with 80 cases, included all patients whose gamma-GT levels were more than 30 mU/ml and serum-bilirubin less than 1.2 mg/ml, with alkaline phosphatase levels between 90-180 mU/ml. Group II included those with alkaline phosphatase levels higher than 180 mU/ml (57 cases). All over incidence of dissociated cholestasis was 13.82%. Main causes in group I were infectious diseases, mainly pneumonias and urinary infections and congestive cardiac failure. In group II, neoplasias such as Hodgkin's disease and epithelial metastases and obstructions of the biliary tract such as vesicular or choledocal litiasis were the main causes. Transaminase levels underwent variable increases according to the different entities, without there being any difference between the two groups. The physiopathology as well as the anatomopathological aspects which could originate the syndrome are discussed.