[Modifications of serum proteins in various human parasitic diseases].
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Biomedical subjects
Publications and source records attributed to A Colea.
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The frequency of intestinal parasitoses among subjects coming from warm countries is high and its range is similar to that found by other parasitologists in Europe as well as by those who made investigations in groups of individuals in various warm countries. Bearing in mind the pathogenous role--even limited--of certain parasites, their systematic detection and the treatment of every individual infested with parasites appears necessary. The hereby investigations point out the importance of a complex coproparasitologic examination and the high efficiency of some special diagnosis methods. Every laboratory must perform in rarallel several ovoscopic and larvoscopic methods of investigation in view of an accurate parasitologic diagnosis or for a prophylactic control of subjects coming from warm countries. The high frequency of ankylostomiasis raises peculiar problems related to its systematic detection and its compulsory treatment up to the parasitologic sterilization, bearing in mind the past evolution in Rumania of an underground focus, which does not exist any more, having been entirely eradicated.
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In a lot of 3 patients with olfactory meningioma, one patient drew particular attention by the particularities of its evolution, which was asymptomatic for a long time and atypical. The disease started at the age of 38 with asthenia, headaches, dizziness and X-ray images of left parasellar calcified brain tumour, without neurological signs of a focus at any of the repeated clinical or paraclinical examinations. After eight years focal signs appears: left pyramidal irritation, absences, left hyposmia, without altered visual acuity or conclusive scintigraphic and EEG alterations. Left carotid arteriography indicated a space-occupying process. The disease progressed slowly with left hemiparesis and corresponding effects. A diagnosis of "left olfactory meningioma" was established in the Neurosurgical Clinic, Bucharest. The situation deteriorated in 1977: total left anosmia, Jacksonian seizures, sometimes generalized, uncinate fits, paroxysmal headaches, amnesia disturbances and marked right hemiparesis. Recent scintigraphic and EEG alterations likewise lent support to a diagnosis of brain tumour. The existence of calcified, asymptomatic, trailing brain tumours, with an atypical and late evolution of unilateral olfactory meningioma, without Foster-Kennedy syndrome, demands from the beginning close surveillance and complex investigations, since a prolonged absence of anosmia and focal phenomena does not exclude the possibility of a meningioma of the olfactory groove, and may often lead to errors of diagnosis.
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