[Modification of the auricular refractory period by suppression of cardiomoderating innervation in chloralosed dogs].
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Biomedical subjects
Publications and source records attributed to A Combre.
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In the dog in chronic atrio-ventricular dissociation, pentobarbital at a dose of 25 mg/kg causes atrial tachycardia, but does not change the ventricular frequency. The vagolytic effect of pentobarbital explains this phenomenon. The pronounced vagal tonus seen in the Keith-Flack node, is not seen in the ventricle. Chloralose at a dose of 80 mg/kg i.v. does not alter atrial frequency but depresses ventricular frequency, in a significant way, for 40 min.
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