PubMed Health⌕ Search

Biomedical subjects

A Cope

Publications and source records attributed to A Cope.

21 records · Page 2Linked to original sources

Adequacy of senior registrar training in accident and emergency medicine over the last 5 years.

This study investigated the limitations of the present Senior Registrar training programmes in A&E Medicine. A completed questionnaire was returned from 46 of the 48 Consultants who had taken up post in the last 5 years and had themselves studied on one of the established training programmes. The positive views of the clinical training contrast sharply with the administrative and managerial components. Around 80% of the new Consultants had no training in clinical budgeting or ordering equipment and only half had experience of appointing staff and organizing locums. This is worrying as over 63% had or are currently facing staffing problems and 69% have financial or equipment difficulties. A more active training programme in A&E administration and management is recommended.

Curriculum↗

A pharmacokinetic study of the recommended dosing schedules of Theo-Dur and Uniphylline.

Theo-Dur, 300 mg twice daily, and Uniphylline, 600 mg once daily taken with food were compared in an open cross-over study in healthy volunteers. Uniphylline had significantly (P less than 0.001) higher peaks, lower troughs and wider variation in theophylline concentrations than Theo-Dur. Peak plasma concentrations were reached earlier for Theo-Dur but the difference failed to reach statistical significance (0.05 less than P less than 0.1). There was no significant difference between the two drugs in area under the plasma concentration time curve. Therapeutic occupancy lasted significantly longer (P less than 0.05) with Theo-Dur; eight volunteers attained 24 h therapeutic occupancy after administration of Theo-Dur compared to 4 h with Uniphylline.

Adult↗