PubMed Health⌕ Search

Biomedical subjects

A Coutselinis

Publications and source records attributed to A Coutselinis.

15 recordsLinked to original sources
PubMed1978

The diagnosis of organophosphorus fatal intoxication by the AChE activity in CSF.

A preliminary test for the diagnosis of intoxications with organophosphorous pesticides in fatal cases is described, based on the fact that these compounds inhibit AChE activity. For this purpose we measured AChE activity in CSF in 30 samples from fresh bodies autopsied after traffic accidents and in six after poisoning with organophosphorous insecticides. In order to exclude any other effect on the postmortem inactivation of the enzyme e.g. putrefaction we determined the AChE activity under different conditions. Thus we confirmed that in the reference samples, regardless the conditions, the activity of the enzyme was detectable at least 48 h after death, while in cases of poisoning the detection of AChE was inevitable early after death.

Acetylcholinesterase↗
PubMedDate not supplied

Concentration levels of 2,4-D and 2,4,5-T in forensic material.

Concentration levels, of 2,4-D and 2,4,5-t in blood and viscera in a case of fatal intoxication with "Tributon" are given. Since the toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-t), widely used as herbicides in domestic and agricultural situations is very low, little information exists on human toxicology and particularly on analytical data in forensic material in cases of fatal poisoning. The reason of this paper is to provide further information on the concentration levels of these compounds in viscera in cases of fatal, accidentally or suicidal, poisoning.

2,4,5-Trichlorophenoxyacetic Acid↗