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A Craven

Publications and source records attributed to A Craven.

5 recordsLinked to original sources
PubMed1990

A controlled trial of a low sodium, low fat, high fibre diet in treated hypertensive patients: the efficacy of multiple dietary intervention.

An 8-week combination low sodium, low fat, high fibre diet was compared to the individual components of this diet in a controlled trial using 193 patients already on treatment for essential hypertension. No significant changes were observed in the high fibre group. The low sodium group showed a decrease in systolic blood pressure which was close to significance. The low fat group showed a small but significant decrease in seated diastolic blood pressure and weight. The combination group showed larger and highly significant decreases in seated and standing systolic blood pressures, seated diastolic blood pressure and weight, as well as a significant reduction in standing diastolic blood pressure. We conclude that multiple dietary intervention in this case in the form of a low sodium, low fat, high fibre diet, is more effective than any single dietary intervention and is useful in patients already on medication.

Adult↗
PubMed1990

The effect of a combination low sodium, low fat, high fibre diet on serum lipids in treated hypertensive patients.

The effect of a combination low sodium, low fat, high fibre diet on serum lipids in 184 treated hypertensive patients was analysed in a controlled trial. The combination diet caused a small but significant reduction in serum triglyceride and total cholesterol. This was apparently due to the low fat component of the diet, since a low fat diet alone also caused a similar reduction in total cholesterol, whereas a high fibre diet or a low sodium diet alone caused no significant changes in serum lipids. Analysis of the medication subgroups suggests that diuretics may allow more favourable changes in lipid profile than betablockers. The combination diet and the low fat diet both caused a significant reduction in HDL cholesterol. Thus there was no significant change in the HDL ratio for the combination group and a significant decrease in this ratio for the low fat group. Furthermore the magnitude of changes in total and LDL cholesterol in the low fat and combination groups was much smaller compared to previously observed changes in untreated patients. The overall limited benefit of the combination diet, and possibly adverse effect of the low fat diet, may contribute to the limited effect of therapeutic intervention on mortality from ischaemic heart disease seen in previous studies.

Adrenergic beta-Antagonists↗